A clinical trial to study the effects of drugs i.e. intravenous nalbuphine and dexmedetomidine as premedication on emergence agitation in adult patients undergoing abdominal surgery.
- Conditions
- Delirium due to known physiological condition,
- Registration Number
- CTRI/2020/11/029347
- Lead Sponsor
- GGS Medical College and Hospital Faridkot Punjab
- Brief Summary
Emergence agitation (EA) is one of the most common complications after general anaesthesia. EA comprises of agitation, confusion,disorientation or violent behaviour in the early phase of recovery from generalanaesthesia. Nalbuphine and dexmedetomidine are the two drugs we are going to compare on the basis of incidence, severity, hemodynamic variability and side effects. This study will be having two groups with sample size of 40 in each group including both males and females of age between 18 to 55 years and excluding patients with history of anaphylaxis or allergy to the study drugs and patients refusing for consent etc.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 80
Patients of age between 18 to 55 years, undergoing abdominal surgery under General anaesthesia (GA).
- 1.Duration of surgery ≤ 1 hour.
- 2.Patient having renal, hepatic, cardiovascular and cerebral dysfunction.
- 3.History of anaphylaxis or allergy to the study drugs 4.BM I >30 kg/m2.
- 5.Psychiatric disorders or drug abuse.
- •Patients refused to participate in study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of IV nalbuphine and dexmedetomidine on incidence of EA. Hourly monitoring till 12 hours.
- Secondary Outcome Measures
Name Time Method 1.Severity of EA. 2.NRS score for Post Operative Pain (POP) assessment.
Trial Locations
- Locations (1)
GGS Medical College and Hospital, Faridkot, Punjab
🇮🇳Faridkot, PUNJAB, India
GGS Medical College and Hospital, Faridkot, Punjab🇮🇳Faridkot, PUNJAB, IndiaGurwinder KaurPrincipal investigator9464311295gkmalhi95@gmail.com