A clinical trial to study the effects of drugs i.e. intravenous nalbuphine and dexmedetomidine as premedication on emergence agitation in adult patients undergoing abdominal surgery.

Not yet recruiting

• Conditions: Delirium due to known physiological condition,

• Registration Number: CTRI/2020/11/029347
• Lead Sponsor: GGS Medical College and Hospital Faridkot Punjab

Brief Summary

Emergence agitation (EA) is one of the most common complications after general anaesthesia. EA comprises of agitation, confusion,disorientation or violent behaviour in the early phase of recovery from generalanaesthesia. Nalbuphine and dexmedetomidine are the two drugs we are going to compare on the basis of incidence, severity, hemodynamic variability and side effects. This study will be having two groups with sample size of 40 in each group including both males and females of age between 18 to 55 years and excluding patients with history of anaphylaxis or allergy to the study drugs and patients refusing for consent etc.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-27
• Last Update Posted: 2020-11-27

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients of age between 18 to 55 years, undergoing abdominal surgery under General anaesthesia (GA).

Exclusion Criteria

• 1.Duration of surgery ≤ 1 hour.
• 2.Patient having renal, hepatic, cardiovascular and cerebral dysfunction.
• 3.History of anaphylaxis or allergy to the study drugs 4.BM I >30 kg/m2.
• 5.Psychiatric disorders or drug abuse.
• •Patients refused to participate in study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the effect of IV nalbuphine and dexmedetomidine on incidence of EA.	Hourly monitoring till 12 hours.

Secondary Outcome Measures

Name	Time	Method
1.Severity of EA.	2.NRS score for Post Operative Pain (POP) assessment.

Trial Locations

Locations (1)

GGS Medical College and Hospital, Faridkot, Punjab; 🇮🇳 Faridkot, PUNJAB, India

GGS Medical College and Hospital, Faridkot, Punjab

🇮🇳Faridkot, PUNJAB, India

Gurwinder Kaur

Principal investigator

9464311295

gkmalhi95@gmail.com