The Association Between Autoimmune or Inflammation and Thyroid Disease

Recruiting

• Conditions: THYROTOXICOSIS

• Registration Number: NCT02886949
• Lead Sponsor: Taichung Veterans General Hospital

Brief Summary

This study aims to evaluate the effects of thyroid functions on energy homeostasis and inflammation.

Detailed Description

The subjects were enrolled for evaluation of thyroid functions. The associations between thyroid function and energy homeostasis and inflammation will be assessed.

Study Timeline

• Study Start: 2011-11
• Study First Submitted: 2015-09-02
• Study First Submitted QC: 2016-08-26
• Study First Posted: 2016-09-01
• Status Verified: 2020-01
• Last Update Submitted: 2020-01-04
• Last Update Posted: 2020-01-07
• Primary Completion: 2020-12
• Study Completion: 2024-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Subjects visits outpatient department due to a suspicion of thyroid disease

Exclusion Criteria

• Psychological disorders, severe inflammatory or infection diseases.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
brain-derived neurotrophic factor	3 months	BDNF

Secondary Outcome Measures

Name	Time	Method
vascular cell adhesion molecule 1 (VCAM-1)	3 months	Inflammation
C-reactive protein (CRP)	3 months	Inflammation
Orexin	3 month	Psychological assessment
Zung Self-Rating Depression Scale (Zung SDS)	3 month	Depressive symptom
Body composition	3 month	fat component
ankle brachial index (ABI)	3 months	Arterial stiffness
pulse wave velocity (PWV)	3 months	Arterial stiffness
mean arterial pressure (MAP)	3 months	Arterial stiffness

Trial Locations

Locations (1)

Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital; 🇨🇳 Taichang, Taiwan