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临床试验/NCT02886949
NCT02886949招募中不适用

The Relationship of Vascular Cell Adhesion Molecule 1, C-reactive Protein, Brain-derived Neurotrophic Factor, Orexin and Depressive Symptoms in the Subjects With Thyroid Disease

Taichung Veterans General Hospital1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2011年11月最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
500
试验地点
1
主要终点
brain-derived neurotrophic factor

研究概览

简要总结

This study aims to evaluate the effects of thyroid functions on energy homeostasis and inflammation.

详细描述

The subjects were enrolled for evaluation of thyroid functions. The associations between thyroid function and energy homeostasis and inflammation will be assessed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Subjects visits outpatient department due to a suspicion of thyroid disease

排除标准

  • Psychological disorders, severe inflammatory or infection diseases.

结局指标

主要结局

brain-derived neurotrophic factor

时间窗: 3 months

BDNF

次要结局

  • vascular cell adhesion molecule 1 (VCAM-1)(3 months)
  • C-reactive protein (CRP)(3 months)
  • Orexin(3 month)
  • Zung Self-Rating Depression Scale (Zung SDS)(3 month)
  • Body composition(3 month)
  • ankle brachial index (ABI)(3 months)
  • pulse wave velocity (PWV)(3 months)
  • mean arterial pressure (MAP)(3 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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