Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma

Completed

• Conditions: Normal Tension Glaucoma; High Tension Glaucoma

• Registration Number: NCT01488032
• Lead Sponsor: Technische Universität Dresden

Brief Summary

The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.

Detailed Description

It is till now not definitely clear whether normal- and high-tension glaucoma are different forms of the same disease and whether they have similar pathogenetic mechanisms. Spectral domain optical coherence tomography (SD-OCT) is supposed to objectively evaluate retinal nerve fiber layer (RNFL) thickness. The investigators propose a study to compare the RNFL in patients with normal- and high-tension-glaucoma. In order to exclude other possible differences,which could influence the results, only patients with similar structural optic nerve head damage in both groups will be compared.

Study Timeline

• Study Start: 2011-03
• Primary Completion: 2011-11
• Study Completion: 2011-11
• Status Verified: 2011-12
• Study First Submitted: 2011-12-01
• Study First Submitted QC: 2011-12-07
• Study First Posted: 2011-12-08
• Last Update Submitted: 2011-12-08
• Last Update Posted: 2011-12-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• persons over 18 years
• men or women
• with normal- and high-tension glaucoma

Exclusion Criteria

• cataract
• cloudy cornea and other conditions with bad visualisation quality of optic nerve head
• optic nerve atrophy except glaucomatous

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
RNFL in different segments	up to 9 Months	RNFL in upper, lower, temporal and nasal segments