A randomized, double-blind, non-inferiority trial evaluating the efficacy and safety of two different mouthrinses on patients with gingival inflammation.
Not Applicable
- Conditions
- periodontal diseaseperiodontal inflammationGingivitisSARS-CoV-2 infectionAlternative and Complementary Medicine - Herbal remediesOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon
- Registration Number
- ACTRN12622000215729
- Lead Sponsor
- Polytechnic University of Marche
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 82
Inclusion Criteria
minimum of 20 teeth, good physical health, gingivitis, periodontitis stages I or II
Exclusion Criteria
1) active caries
2) wearers of dentures and of orthodontic appliances;
3) severe malocclusion;
4) use of oral antiseptics in the previous three months;
5) subjects with medical disorders;
6) undergoing antibiotic or other antimicrobial therapy in the previous 3 months;
7) the presence of any systemic disease that could alter the production or composition of the saliva or dental plaque;
8) individuals with an allergy to any ingredients used in the study;
9) pregnant women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The bleeding index on 6 surfaces using full mouth bleeding score.<br>[Baseline; 2 weeks post intervention commencement]
- Secondary Outcome Measures
Name Time Method The plaque index on 6 surfaces using full mouth plaque score (FMPS).<br><br>[Baseline; 2 weeks post intervention commencement];The patient taste appreciation using 10-cm Visual Analogue Score (VAS).<br>[Baseline; 2 weeks post intervention commencement];The extrinsic stain using modified Lobene stain index.[Baseline; 2 weeks post intervention commencement];Detection and concentration of SARS COV-2 [Baseline; 2 weeks post intervention commencement]