Comparison of vortioxetine and sertraline for treatment of major depressive disorder in elderly patients
Phase 3
Recruiting
- Conditions
- Major Depressive Disorder.Major depressive disorder, single episode, moderateF32.1
- Registration Number
- IRCT20090117001556N118
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Presence of Major Depressive Disorder based on DSM-5 criteria
Baseline Hamilton Depression Rating Scale (HAM-D) (17-item) score of at least 19
Age at least 60 years old
Exclusion Criteria
Presence of psychosis
Any other mental disorder
Receiving psychotropic medications
Receiving any antidepressants during past one month or ECT during past two months
Hypothyroidism
Cardiovascular disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Baseline and weeks 3 and 6. Method of measurement: By Hamiltion Depression Rating Scale 17-Item.
- Secondary Outcome Measures
Name Time Method