Effect of Dihydrocapsiate on Energy Expenditure in Women
Not Applicable
Completed
- Conditions
- Obesity
- Interventions
- Dietary Supplement: Dihydrocapsiate
- Registration Number
- NCT01773356
- Lead Sponsor
- Ellen Evans
- Brief Summary
The objective of this study is to test the effect of dihydrocapsiate on energy expenditure in women.
- Detailed Description
Capsaicin, a substance found in chili pepper, is known to stimulate thermogenesis. Dihydrocapsiate, a capsinoid, found in the non-pungent CH-19 sweet pepper has similar thermogenic effects without the gastrointestinal side effects. The objective of this project is to test the effect of 12 weeks of daily consumption of 9 mg dihydrocapsiate on resting energy expenditure relative to baseline when compared to a control group consuming products without DCT.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 126
Inclusion Criteria
- BMI: 18.5-34.5 kg/m2
- Good general health
- Low to mild physical activity
- Willing to maintain habitual diet and physical activity patterns throughout the study period
- Premenopausal and cycling regularly or using oral contraceptives
- Willing to attend study visits only during the follicular phase or bleed phase of their menstrual cycle
- Understands study procedures and signs forms providing informed consent to participate in the study
- Have spoken and written English literacy
Exclusion Criteria
- Diabetes mellitus or any conditions that might affect energy metabolism
- Weight change ±2 kg over previous three months
- Known sensitivity or allergy to ingredients of the study products
- Non-breakfast eater
- Recent use of antibiotics
- History of smoking during the six months prior to study
- Recent signs or symptoms of infection, including cold or flu-like symptoms
- Concurrent or recent intervention study participation
- Instability in breathing patterns or energy expenditure measures
- History of drug or alcohol abuse
- Lipid-lowering, anti-hypertensive or anti-inflammatory steroid medication use
- Weight loss medication
- Pregnant or lactating
- Unwilling to be randomized to any experimental group and unable to meet all requirements of the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Dihydrocapsiate 9 mg/d Dihydrocapsiate 9 mg/d of Dihydrocapsiate will be consumed in ready to ear cereal, cereal bars or crackers Placebo 0 mg/d Dihydrocapsiate 0 mg/d of Dihydrocapsiate will be consumed in ready to ear cereal, cereal bars or crackers
- Primary Outcome Measures
Name Time Method Resting Energy Expenditure Change from Baseline at 12 weeks
- Secondary Outcome Measures
Name Time Method Thermic effect of feeding Change from baseline at 12 weeks Body Composition Change from baseline at 12 weeks
Trial Locations
- Locations (1)
University of Georgia, Department of Kinesiology
🇺🇸Athens, Georgia, United States