Effects of Soluble Fiber on Blood Pressure: A Meta-analysis of Randomly-controlled Trials
- Conditions
- Blood Pressure
- Registration Number
- NCT02670967
- Lead Sponsor
- Unity Health Toronto
- Brief Summary
The present study conducted a meta-analysis of 22 randomly controlled trials to assess the effects of soluble fiber intake on blood pressure in human subjects.
Using the Cochrane Handbook for Systematic Reviews of Intervention, a systematic review and meta-analysis was conducted. Information regarding study methods, characteristics, mean BP and standard deviations were extracted The data from each study were pooled using a random effects model to estimate the effects of soluble fiber consumption on blood pressure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
- Randomized Controlled Trials
- Parallel or Crossover Design
- Duration: >3 weeks
- Human trials
- Viscous (soluble) fiber
- Viable endpoint data
- Articles published in English
Exclusion Criteria
- Non-human
- Non-randomized
- Lack of control
- Less than 4 weeks in duration
- No viable endpoint data
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic Blood Pressure 4 weeks Diastolic Blood Pressure 4 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre
🇨🇦Toronto, Ontario, Canada