A community based study to determine the feasibility of remodelling the diagnosis and management of liver disease in primary care to improve patient outcomes and reduce service delivery costs

niversity of Southampton (UK)0 sites910 target enrollmentAugust 22, 2013

Overview

2018 results in https://www.ncbi.nlm.nih.gov/pubmed/30576330 2. 2019 qualitative results in doi: 10.1136/bmjopen-2018-028591 (added 12/05/2020)

Registry

who.int

Start Date

August 22, 2013

End Date

December 31, 2021

Last Updated

5 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity of Southampton (UK)

•Pre\-Intervention Audit and Post\-Intervention Audit
•1\. Elevated ALT (above ULN), other abnormal liver function test (Alk Phos or bilirubin above ULN, or Albumin
•Intervention Module 1
•1\. Clinical liver disease
•2\. Any patient newly identified by the practice with suspected liver disease in the one year of the prospective phase.
•Intervention Module 2
•1\. All patients identified with a positive cTL on tests in the previous 6m
•A sample from each of the following groups:
•1\. pre\-existing abnormalities in liver function but without liver diagnosis and management plan identified in the practice audit
•2\. Type 2 diabetes

•Pre\-Intervention Audit and Post\-Intervention Audit:
•1\. Patients with known terminal illness.
•Intervention Module 1:
•1\. Patients with known terminal illness.
•Intervention Module 2:
•1\. Patients with known terminal illness.
•2\. Patients with alcohol misuse will be enrolled via Module 3 where appropriate
•Intervention Module 3:
•1\. Patients with known terminal illness
•2\. Patients identified on GP system as having pre\-existing liver disease.