NCT03125655招募中不适用
Regulation of Inflammatory Genes in Psoriasis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Inflammatory genes
研究概览
简要总结
Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 19 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of psoriasis
- •Must be age 19 or older.
- •Must be Fitzpatrick skin type I, II, III, IV, V, VI.
排除标准
- •Subjects who do not have photosensitive disease and are not on photosensitizing medications.
- •Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
- •Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
- •Subjects who are pregnant.
结局指标
主要结局
Inflammatory genes
时间窗: 1 day
TNF-alpha , IFN-alpha , IL-6, IL-8, IL-12 , IL-23, IL-4, IL-5 and IL-10
次要结局
未报告次要终点
研究者
Nabiha Yusuf
Professor
University of Alabama at Birmingham
研究点 (2)
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