Randomized Trial of Multiplex real-time PCR-based antibiotic therapy for severe bloodstream infections

Not Applicable

Completed

• Conditions: bacteremia

• Registration Number: JPRN-UMIN000039433
• Lead Sponsor: Hitachi General Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-08
• Study Completion: 2020-10-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up continuing
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

1) Suspected persistent bacteremia (positive blood cultures of the same bacteria based on gram stain examination) within the past week. 2) If no bacteria is shown on gram stain examination despite positive blood cultures. 3) If more than 48 hours have passed after positive blood cultures. 4) Receiving palliative care without antibiotic therapy. 5) If patients are not hospitalized in the ICU/HCU (due to death or transfer to another hospital/department).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration between the identification of positive blood cultures and the initiation of appropriate antibiotic therapy.

Secondary Outcome Measures

Name	Time	Method
1) 28 day-mortality 2) Duration of ICU stay 3) Duration of hospital stay 4) Total cost of antimicrobial agents