ACTRN12607000301460已完成3 期
A randomised clinical trial to compare the efficacy of nebulized N-acetylcysteine and normal saline in improving sputum quality and diagnostic yield in patients with chest infections.
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 190
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Diagnosis
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 ot stated（—）
- 性别
- All
入选标准
- •Differential diagnosis inclusive of lower respiratory tract infection as determined by the treating physician (eg. cough, fever, pleuritic chest pain, dyspnoea, decreased breath sounds, bronchial breath sounds, crackles on auscultation) ·A sputum sample is to be collected in the ED.
排除标准
- •Inability to co-operate or consent due to debility, significant illness, language barriers, altered consciousness (as determined by the ED or study staff)·Refusal to participate·Pregnancy or breast-feeding·Known allergy to NAC·Presence of significant hepatic or renal failure·Presence of other significant co-morbidities eg. HIV, immunocompromised, cystic fibrosis, bronchiectasis·CXR suggestive of TB·Recent hospital admission within the previous 14 days inclusively·Current treatment with >10mg prenisolone daily for more than 1 month inclusively
研究者
相似试验
已完成
4 期
Intravenous midazolam-droperidol (combination), droperidol (only) or olanzapine (only) for the acutely agitated patient:A multi-centre, randomised, double-blind, controlled, clinical trialACTRN12614000980639Austin Hospital342
已完成
4 期
Topical alkane vapocoolant spray versus subcutaneous lignocaine injection for reducing the pain of intravenous cannulation: a randomised, controlled, clinical trialACTRN12608000414314Austin Health220
已完成
不适用
EMLA versus N2O for analgesia during intravenous cannulation of children in the emergency departmentPainAnaesthesiology - AnaestheticsACTRN12606000121561orthern Hospital, VIC100
已完成
4 期
The effects of droperidol and olanzepine in addition to midazolam for sedating very agitated patients: a multi-centre, randomised, controlled clinical trialsevere agitationMental Health - Other mental health disordersOther - Conditions of unknown or disputed aetiology (such as chronic fatigue syndrome/myalgic encephalomyelitis)ACTRN12607000591459Austin Hospital320
尚未招募
1 期
A RANDOMISED CLINICAL TRIAL TO COMPARE THE EFFICACY OF SINGLE INJECTION AND TRIPLE INJECTIONS USING A COSTOCLAVICULAR APPROACH FOR INFRACLAVICULAR BRACHIAL PLEXUS BLOCK FOR UPPER LIMB SURGERYCTRI/2023/09/058121Shri B M Patil medicaal college hospital and Reaseach centre