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Clinical Trials/NCT05388045
NCT05388045
Enrolling by Invitation
N/A

Piloting a Patient-Reported Outcome Measure for Opioid Use Disorder Recovery in a Clinical Setting

Brandeis University1 site in 1 country100 target enrollmentApril 14, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Substance Use Disorders
Sponsor
Brandeis University
Enrollment
100
Locations
1
Primary Endpoint
Change in reported health related quality of life (4-point scale), assessed via CDC HRQOL questionnaire
Status
Enrolling by Invitation
Last Updated
2 years ago

Overview

Brief Summary

Performance measure can improve quality of care at the patient, provider, and systems level of care, and patient-reported outcome measures bring a needed patient-centered focus. Recovery has been difficult to measure for people with substance use disorders, and is more challenging in the context of opioid use disorders (OUD) and treatment medications. This study will examine a recovery patient-reported outcome measure to determine if patients and clinicians find it useful and acceptable in the clinical context, and if it leads to improved outcomes.

Detailed Description

The pilot clinical trial will test the newly developed Recovery Patient-Reported Outcome Measure ("Recovery PROM") and approach with patients and clinicians in an office-based opioid medication treatment program (known as office-based opioid treatment (OBOT), medication-assisted treatment (MAT) or medications for OUD (MOUD)), in the specific context of buprenorphine treatment. Aims This is a pilot study to assess the feasibility of implementing the Recovery PROM into the workflow of a clinical setting, assess its initial effectiveness, and evaluate its value to patients and clinicians. The aims are as follows: 1. Work with a clinical partner to assess and refine the draft Recovery PROM, and examine feasibility and implementation (e.g., workflow, data transfer issues) related to its use in a clinical setting. 2. Determine initial effectiveness of the Recovery PROM for improving patient outcomes (self-efficacy, health-related quality of life, patient-provider relationship, social determinants of health, substance use) and facilitating self-directed care and patient-centered shared decision-making. 3. Evaluate and update (if needed) the Recovery PROM in terms of recovery while on OUD medication treatment, patient characteristics, and clinical workflow. Hypotheses Although this pilot study is primarily for information gathering, and ultimately refinement of the Recovery PROM and approach, the study has two broad hypotheses. H1. Patients and clinicians will find the Recovery PROM to be a useful tool for patient recovery. H2. Patient self-efficacy, shared decision-making, patient-provider relationship, and health-related quality of life will improve and substance use will decrease with the use of the Recovery PROM.

Registry
clinicaltrials.gov
Start Date
April 14, 2022
End Date
November 1, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sharon Reif

Professor

Brandeis University

Eligibility Criteria

Inclusion Criteria

  • Taking buprenorphine for OUD treatment, in current episode of care at clinical partner site, for at least 6 weeks but less than 3 years.
  • Able and willing to provide informed consent.
  • Able to read English, to provide informed consent and complete study instruments.
  • Able to use a smart phone to complete study instruments \[phones with data plan will be provided for those without\].

Exclusion Criteria

  • Patients who do not meet inclusion criteria.

Outcomes

Primary Outcomes

Change in reported health related quality of life (4-point scale), assessed via CDC HRQOL questionnaire

Time Frame: 3 months after baseline, 6 months after baseline

Centers for Disease Control \& Prevention (CDC) Health Related Quality of Life (HRQOL) questionnaire, single item ranging from excellent (score=1) to poor (score=5).

Change in number of days mental/physical health were not good (in past 30 days), assessed via CDC HRQOL questionnaire.

Time Frame: 3 months after baseline, 6 months after baseline

CDC Health Related Quality of Life (HRQOL) questionnaire, separate items for mental and physical health, single item measuring the number of days out of 30, where 0 is no days (better) and 30 is daily (worse).

Change in reported self-efficacy for managing chronic conditions, assessed via PROMIS Self-Efficacy measure

Time Frame: 3 months after baseline, 6 months after baseline

Patient-Reported Outcomes Measurement Information System (PROMIS) Self-Efficacy scale, a series of 10 questions each on a 5-point scale, ranging from not at all confident (score=1) to very confident (score=5).

Change in patient-clinician alliance, assessed via WAI-SR

Time Frame: 3 months after baseline, 6 months after baseline

Working Alliance Inventory-Short Revised (WAI-SR): Patient-clinician alliance for tasks and goals of treatment, and effective relationship. This scale is a series of 12 items, with responses ranging from seldom (score=1) to always (score=5).

Secondary Outcomes

  • Social determinants of health, assessed via PRAPARE(3 months after baseline, 6 months after baseline)
  • Substance use past 30 days, assessed via modified ASI Alcohol and Drug module(3 months after baseline, 6 months after baseline)

Study Sites (1)

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