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Clinical Trials/NCT05782114
NCT05782114
Not yet recruiting
Not Applicable

Efficacy Of Extracorporeal Shockwave Therapy On Ultrasonographic Changes, Pain, Function And Grip Strength In De Quervain Tenosynovitis

Cairo University1 site in 1 country60 target enrollmentApril 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
De Quervain Disease
Sponsor
Cairo University
Enrollment
60
Locations
1
Primary Endpoint
Ultrasonographic Changes: Thickness in tendons:
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

The current study will be conducted to explore the efficacy of ESWT on ultrasonographic changes, pain intensity level, upper limb function and hand grip strength in patients with de Quervain tenosynovitis.

Detailed Description

De Quervain tenosynovitis (DQT) is a painful condition involving the tendons of the abductor pollicis longus (APL) and extensor pollicis brevis (EPB). The pathogenesis is generally defined as a stenosing condition of the first dorsal compartment of the wrist, characterized by thickening of the extensor retinaculum of APL and EPB, which can cause tendon gliding difficulties and impingement between the tendons and their fibrous sheaths. The prevalence rate of DQT in the general population is 0.5% for males and 1.3% for females, with peak prevalence at the age of 40-60 years. Female prevalence is 6 to 10 times higher than that in men. De Quervain tenosynovitis is a repetitive strain injury consider postures where the thumb is held in abduction and extension to be predisposing factors. De Quervain tenosynovitis incidence increased by virtue of modern life conditions such as excessive computer use and increased use of cellular phones. However, little research has been carried out to determine the therapeutic effects of ESWT in DQT, and up till now, there is a gap in literature that explore ESWT efficacy on ultrasonographic changes of DQT. So This current study will be conducted to explore the efficacy of ESWT on ultrasonographic changes, pain intensity level, upper limb function and hand grip strength in patients with de Quervain tenosynovitis. Sixty patients from both genders will be involved in this study and will be randomly subdivided into two equal groups in number. First Group (A) (Experimental Group) will receive radial Extracorporeal Shockwave therapy plus Traditional physical therapy program and the second Group (B) (Control Group): This group will receive Traditional physical therapy program.

Registry
clinicaltrials.gov
Start Date
April 1, 2023
End Date
August 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mostafa Gomaa Mahmoud Ali

Assistant Lecturer

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Age from 18 to 65 years
  • Both genders (males and females).
  • Normal BMI ranges between 18.5:24.9 kg/m
  • Patients will be referred from an orthopedist with diagnosis of DQT.
  • Chronic pain more than 2 months.
  • No history of undergoing physiotherapy modalities or corticosterone injection therapies for any reasons during the past month.
  • De Quervain tenosynovitis patients will be diagnosed based on the standard criteria, including pain and tenderness in the lateral wrist and a positive result for the Finkelstein test.

Exclusion Criteria

  • History of undergoing physiotherapy modalities or corticosterone injection therapies for any reason during the past month.
  • Subjects with other neurological disorders rheumatologic diseases causing wrist pain.
  • History of fracture or surgery on the hand.
  • Severe trauma, and coagulation disorders.

Outcomes

Primary Outcomes

Ultrasonographic Changes: Thickness in tendons:

Time Frame: Up to Four weeks

Ultrasonography which is a valid and reliable measure to evaluate tendon structural changes including: 1. Tendon thickness APL \& EPB tendons in mm. 2. Thickness of hypoechoic area in mm.

Ultrasonographic Changes: Color Doppler activity

Time Frame: Up to Four weeks

Ultrasonography

Secondary Outcomes

  • Pain intensity level assessment :(Up to Four weeks)
  • Pinch grip Strength assessment:(Up to Four weeks)
  • Handgrip Strength assessment:(Up to Four weeks)
  • Assessment of upper limb function:(Up to Four weeks)

Study Sites (1)

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