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临床试验/NCT05830006
NCT05830006尚未招募不适用

Indications and Evaluation of Microfat Grafting in Cleft Lip Nasal Deformities

Assiut University0 个研究点目标入组 30 人开始时间: 2025年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
主要终点
Anthropometric measurement for the nose in relation to face

研究概览

简要总结

Aim of the work:

The study will be conducted to investigate the efficacy of microfat graftinig in cleft lip nasal deformities especially in young patients and those adults who don't need major correction after rhinoplasty.

详细描述

Microfat grafting was used for the first time in 1880, in reconstructive surgery to correct facial deformities, to reconstruct defects post oncological surgery, to treat complex wounds, and to manage scars. Therefore its usage is increasing widely and particularly in maxillofacial and plastic surgeries.

As lipofilling is a potential filler of reference for rhinoplasty and it can be performed on the dorsum, radix, glabella, pre-maxilla, and nasal pyramid. The investigators are suggesting it's use in cleft lip nasal deformities in some special situations.

Imperfections post rhinoplasty are common and there is an increased risk of patient dissatisfaction in revision surgeries. This may be due to a change in the nasal anatomy, the development of scar tissue, the loss of cartilaginous support, the altered blood supply, and the compromised soft tissue envelope. Here comes the role of fat grafting which is a relatively simple and safe procedure to camouflage nose imperfections in filling the subcutaneous tissue, and in improving the skin quality post rhinoplasty.

Microfat grafting appears to be effective for correcting minor irregularities of nasal skin and may be appropriate for patients who cannot undergo revision rhinoplasty. It is also an effective salvage procedure for severely damaged skin of the nose. Injection of cryopreserved fat over several sessions is well accepted by patients because cryopreservation of excess harvested fat grafts for subsequent use makes repeated fat graft harvesting unnecessary. Microfat grafting is not a replacement for, but may be a complement to, modern rhinoplasty techniques.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
5 Years 至 35 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Gender : Both sex will be included in the study.
  • Postcleft lip nose deformities.

排除标准

  • Refusing enrollment into the study.
  • Refusing the surgery.
  • Contraindication to anaesthesia.

结局指标

主要结局

Anthropometric measurement for the nose in relation to face

时间窗: 6 months

Results would be depending on objective and subjective measures : \*Objective assessment by taking photos by anthropometric measurement for the nose in relation to face.

次要结局

  • patient and thier parents satisfaction(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Susanna Nabil Habib

Principal Investigator Resident doctor at plastic and reconstructive surgery department at elmabbara health insurance hospital

Assiut University

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