Study of Social Cognition Processes With Multimodal MRI on Healthy Adult Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 主要终点
- behavioral study with neuroanatomical functional correlates consisting of cognitive activation experiments during functional magnetic resonance imaging
研究概览
简要总结
The study of higher cognitive functions (learning, memory, language, reasoning, decision making) in humans constitutes an interdisciplinary field, which combines neurobiological and neurological, neuropsychological, as well as linguistic and artificial intelligence skills. Historically, the study of patients with cerebrovascular lesions or brain pathologies associated with primary and/or cognitive deficits has produced fundamental knowledge in this area. The development of modern non-invasive investigation techniques of the human brain - such as Structural Magnetic Resonance Imaging (MRI), Diffusion Tensor Imaging, Functional Magnetic Resonance Imaging (fMRI), Positron emission (PET), the study of event-related electrophysiological potentials (ERP) or magneto-encephalography (MEG) - has made it possible to carry out similar studies on healthy subjects, as well as the in-vivo analysis of adaptive and plastic mechanisms of the human brain. Recently, the interest of cognitive neuroscience - this is the name taken by this vast interdisciplinary sector which aims to understand the neural mechanisms underlying human cognitive processes - has been oriented towards the study of decision making in social contexts. Knowledge of the mechanisms underlying these processes is fundamental for the most complete description of the biological bases of human behavior and above all for the optimal development of treatments for brain pathologies, whether surgical, pharmacological or rehabilitation in general.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age between 18 and 35 years old; Monolingual native speakers of Italian; Absence of neurological or psychiatric pathologies that could interfere with carrying out the exam.
排除标准
- •Clinical and/or anamnestic evidence of significant neuropsychiatric or systemic pathologies; Previous head trauma with loss of consciousness
结局指标
主要结局
behavioral study with neuroanatomical functional correlates consisting of cognitive activation experiments during functional magnetic resonance imaging
时间窗: 1 year
次要结局
未报告次要终点
研究者
Chiti Arturo
Professor in Diagnostic Imaging and Radiotherapy Faculty of Medicine and Surgery, Vita-Salute San Raffaele University Director, Department of Nuclear Medicine, IRCCS Ospedale San Raffaele
IRCCS San Raffaele
