Comparative study of hemodynamic effects of bolus and fractionated doses of spinal anesthesia in high risk patients undergoing lower limb surgeries A Randomised controlled double blind prospective study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- At the end of the study we anticipate a clear cut hemodynamic stability in high risk patients till 24 hours
研究概览
简要总结
Ethical committee approval taken. Patient informed consent taken. Patient of ASA3 and 4 groups undergoing lower limb surgeries are randomly allocated into 2 groups by computer based allocation. 2 groups
Group B- Bolus dose of bupivacaine heavy 0.5% 0.2mg/kg with 0.5mcg/kg buprinorphine according to ideal body weight
Group F-- fractionated dose of bupivacaine heavy 0.5% 0.2mg/kg with 0.5mcg/kg buprinorphine according to ideal body weight 2/3rd followed by 1/3rd dose 60 seconds apart.
Blood pressure and time of achieving T10 sensory level and bromage 4 is noted and time of regression of sensory level by 2 dermatomes is noted and bromage 0 is noted.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients belonging to ASA 3 And ASA 4 groups Patients undergoing lower limb surgery.
排除标准
- •Patients not belonging to ASA 3 And ASA 4 groups Patients not undergoing lower limb surgery Patients less than 40 years of age.
结局指标
主要结局
At the end of the study we anticipate a clear cut hemodynamic stability in high risk patients till 24 hours
时间窗: At the end of the study we anticipate a clear cut hemodynamic stability in high risk patients till 24 hours
次要结局
- Increased duration of sensory & motor blockage till twentyfour hours(Increased duration of sensory & motor blockage till 24 hours)
研究者
Spandana gs
SDM college of medical science and hospital