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Clinical Trials/NCT03246165
NCT03246165
Completed
Not Applicable

Incidence, Predictive Factors and Complications of Delirium in Postoperative Cardiac Surgery Elderly Patients

University of Sao Paulo0 sites173 target enrollmentSeptember 1, 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Delirium
Sponsor
University of Sao Paulo
Enrollment
173
Primary Endpoint
Delirium
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Detailed Description

Delirium is a transient and fluctuating course syndrome of acute onset that is characterized by reduced level of consciousness, global cognitive dysfunction, and disorder in the sleep-wake cycle. In patients undergoing cardiac surgery, delirium is a complication that affects 2-57% of the patients, reaching as high as 73% in older subjects. The identification of patients at high risk for delirium is important to deliver proper care and avoid the consequences of this complication. However, previous studies published on the subject have not delivered definitive results in the cardiac surgery setting. Low educational level has also been studied as a risk factor for delirium after surgery but never in a group of cardiac surgery patients that includes a significant rate of illiteracy. The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Registry
clinicaltrials.gov
Start Date
September 1, 2011
End Date
June 30, 2015
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Bruno Caramelli

Associate Professor of Cardiology

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

  • Elective cardiovascular surgery

Exclusion Criteria

  • Blindness,
  • deafness,
  • previous stroke
  • delirium at inclusion, preoperatively
  • creatinine clearance \< 30 ml/min
  • emergency surgery

Outcomes

Primary Outcomes

Delirium

Time Frame: Until hospital discharge or 30 days after surgery, and for up to 18 months.

Delirium was assessed using the Confusion Assessment Method for the Intensive Care Unit

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