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Predictive Factors and Complications of Delirium

Completed
Conditions
Delirium
Age Problem
Surgery--Complications
Registration Number
NCT03246165
Lead Sponsor
University of Sao Paulo
Brief Summary

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Detailed Description

Delirium is a transient and fluctuating course syndrome of acute onset that is characterized by reduced level of consciousness, global cognitive dysfunction, and disorder in the sleep-wake cycle. In patients undergoing cardiac surgery, delirium is a complication that affects 2-57% of the patients, reaching as high as 73% in older subjects.

The identification of patients at high risk for delirium is important to deliver proper care and avoid the consequences of this complication. However, previous studies published on the subject have not delivered definitive results in the cardiac surgery setting. Low educational level has also been studied as a risk factor for delirium after surgery but never in a group of cardiac surgery patients that includes a significant rate of illiteracy.

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
173
Inclusion Criteria
  • Elective cardiovascular surgery
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Exclusion Criteria
  • Blindness,
  • deafness,
  • previous stroke
  • dementia
  • delirium at inclusion, preoperatively
  • creatinine clearance < 30 ml/min
  • emergency surgery
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
DeliriumUntil hospital discharge or 30 days after surgery, and for up to 18 months.

Delirium was assessed using the Confusion Assessment Method for the Intensive Care Unit

Secondary Outcome Measures
NameTimeMethod
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