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临床试验/NCT03246165
NCT03246165已完成不适用

Incidence, Predictive Factors and Complications of Delirium in Postoperative Cardiac Surgery Elderly Patients

University of Sao Paulo0 个研究点目标入组 173 人开始时间: 2011年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
173
主要终点
Delirium

研究概览

简要总结

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

详细描述

Delirium is a transient and fluctuating course syndrome of acute onset that is characterized by reduced level of consciousness, global cognitive dysfunction, and disorder in the sleep-wake cycle. In patients undergoing cardiac surgery, delirium is a complication that affects 2-57% of the patients, reaching as high as 73% in older subjects.

The identification of patients at high risk for delirium is important to deliver proper care and avoid the consequences of this complication. However, previous studies published on the subject have not delivered definitive results in the cardiac surgery setting. Low educational level has also been studied as a risk factor for delirium after surgery but never in a group of cardiac surgery patients that includes a significant rate of illiteracy.

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Elective cardiovascular surgery

排除标准

  • Blindness,
  • deafness,
  • previous stroke
  • delirium at inclusion, preoperatively
  • creatinine clearance < 30 ml/min
  • emergency surgery

结局指标

主要结局

Delirium

时间窗: Until hospital discharge or 30 days after surgery, and for up to 18 months.

Delirium was assessed using the Confusion Assessment Method for the Intensive Care Unit

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Bruno Caramelli

Associate Professor of Cardiology

University of Sao Paulo

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