Bayesian-based propofol infusion advisory tool validatio
Recruiting
- Conditions
- Anesthesiology, propofol infusion, target controlled infusion, medical advisory toolAnesthesiologie, propofol toediening, medisch advies systeem
- Registration Number
- NL-OMON29097
- Lead Sponsor
- Medical University Center Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
•18 years or older
•American Society of Anesthesiology (ASA) Classification 1-4
Exclusion Criteria
•The use of psycho-active drugs
•Alcohol or recreative drug abuse
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the percentage of case time the qCON remains within +/- 10 units from targeted qCO
- Secondary Outcome Measures
Name Time Method •time until loss of consciousness (LOC) from the start of propofol infusion and the amount of propofol used during induction. <br /><br>•The control performance during induction will be studied taking into account the following parameters :<br /><br>•qCONLOC = qCON at the moment of LOC.<br /><br>•TqCON TARGET = observed time required for reaching the target qCON range within +/- 10 units from targeted qCON. <br /><br>•TPEAK, qCON = observed time required for reaching maximal drug effect (lowest qCON value).<br /><br>•qCONPEAK = observed qCON value at tPEAK, qCON.<br /><br>•TEQ = observed time required for finally reaching the target range between 40 and 60 with or without overshoot, also called time to steady-state.<br><br>