PATET Ratio to Rule Out Transient Tachypnea of the Newborn

Completed

• Conditions: Transient Tachypnea of the Newborn

• Registration Number: NCT02965365
• Lead Sponsor: Kayseri Education and Research Hospital

Brief Summary

This study aims to find out whether diagnosis of Transient Tachypnea of the Newborn(TTN) can be predicted via evaluating pulmonary artery Doppler indices.

Detailed Description

Transient Tachypnea of the Newborn(TTN) is the most common diagnosed disease in state of neonatal respiratory distress. However there is not an adequate method to diagnose or rule out TTN.

In several studies pulmonary artery Doppler indices are investigated as the possible indicators of pulmonary function. As a result of these studies, physiological processes in fetal lung maturation were established; pulmonary tissue impedance or resistance decreases with increasing gestational age, leading to increased pulmonary blood flow. In a normal lung maturation process the peak sistolic velocity is reached in midsystole, but in case of any reason disturbing the nornal development process,the peak occurs earlier.

We suggested that TTN, which is a factor increasing pulmonary tissue impedance like respiratory distress syndrome(RDS) and pulmonary hypoplasia, would change pulmonary artery(PA) Doppler indices, thus by the way of evaluating pulmonary artery Doplerr indices, we could predict possible diagnosis of TTN

Study Timeline

• Study Start: 2016-01
• Primary Completion: 2016-09
• Study Completion: 2016-10
• Status Verified: 2016-11
• Study First Submitted: 2016-11-13
• Study First Submitted QC: 2016-11-13
• Study First Posted: 2016-11-16
• Last Update Submitted: 2016-11-16
• Last Update Posted: 2016-11-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 105

Inclusion Criteria

• Singleton pregnancies who delivered beyond 34 weeks gestational age

Exclusion Criteria

• fetal abnormality, chronicle maternal disease, pregnancy complication (preeclampsia, diabetes, intrauterine growth restriction,etc.)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PATET ratio	5 minutes	pulmonary artery acceleration to ejection time ratio

Secondary Outcome Measures

Name	Time	Method
PA PI	2 minutes	pulmonary artery pulsatility index

Trial Locations

Locations (1)

Kayseri Doğumevi; 🇹🇷 Kocasinan, Kayseri, Turkey