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Search genes as factors related with development and phenotype of chronic obstructive pulmonary disease

Not Applicable
Recruiting
Conditions
Diseases of th respiratory system
Registration Number
KCT0000425
Lead Sponsor
Asan Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
2200
Inclusion Criteria

COPD: post-bronchodilator FEV1/FVC < 70% and FEV1 <80% predicted
> 10 pack-years smoking hisotry
Control: Pre-bronchodilator FEV1/FVC > 70% and FEV1 > 80% predicted
and > 10 pack-years smoking history

Exclusion Criteria

1. patients physician-dianosed asthma
2. patients with bronchiectgasis, tuberculosis destroyed lung on chest X
ray
3. segmental atelectasis or obstructive pneumonitis on chest CT
4. combined interstital lung disease on chest CT

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diffrently expressed gene between COPD and control
Secondary Outcome Measures
NameTimeMethod
Different RNA isoform
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