eurobiological mechanisms of early mother-infant-bonding
Phase 2
- Conditions
- Postpartum Bonding DisorderF53Mental and behavioural disorders associated with the puerperium, not elsewhere classified
- Registration Number
- DRKS00014570
- Lead Sponsor
- Institut fuer Medizinische Psychologie im Zentrum fuer Psychosoziale Medizin (ZPM)UniversitaetsKlinikum Heidelberg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 93
Inclusion Criteria
Mothers who gave birth to a healthy child within the last 3-4 month and report problems in bonding with the child.
Depressive symptoms are not an exclusion criteria.
Healthy controls:
Mentally healthy mothers who gave birth to a healthy child within the last 3-4 month and report good bonding with the child
Fathers of the participating infants who give informed content.
Exclusion Criteria
acute suicidality,
bipolare disorder,
schizophrenia,
dementia,
substance abuse or dependency,
MRI-contraindications
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 3, 5 and 12month postpartum<br>- Instructed mother-child-interaction: <br>Face-to-Face-Still-Face-Paradigm<br> -Maternal Bonding using questionnaires and interviews: Interview on postpartal bonding disorders (adapted from I. F. Brockington, Aucamp, & Fraser, 2006), Attachment Style Interview (Bifulco, Moran, Ball, & Bernazzani, 2002), Postpartum Bonding Questionnaire (PBQ-R; Reck et al., 2006), Parental Self Confidence Scale (LMSCS; Lips & Bloom, 1993), Infant Behavior Questionnaire (IBQ; Pauli-Pott, Mertesacker, & Beckmann, 2003)
- Secondary Outcome Measures
Name Time Method 3, 5 and 12 month postpartum:<br>- Neuronale activity of the reward system (in response to stimuli of the own infant)<br>- Stressreagibility (Heartreate and Cortisol in Saliva)<br>- Methylation of the Oxytocin(-receptor-)gene