To study the role of Glycopyrrolate in prevention of fall in blood pressure caused by spinal anaesthesia during surgery in elderly patients.
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/01/039715
- Lead Sponsor
- Department Of Anaesthesiology Sawai Man Singh Medical College And Attached Hospitals Jaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 102
Inclusion Criteria
1.Patient undergoing infraumbilical or lower limb surgery under spinal anaesthesia.
2. Patients willing to give written and informed consent to participate in study.
3. Patient age equal to or more than 60 years.
4. Duration of surgery < 2hrs.
5. Patients belonging to ASA Grade I and Grade II.
Exclusion Criteria
1. H/O allergic reactions to local anaesthetic drugs.
2. Patient with gross spinal deformities.
3. Patient with any bleeding disorder or on anticoagulants.
4. Patient with any cardiovascular disease (Arrhythmias,heart blocks,bradycardia).
5. Patient with local infection at the injection site.
6. Patient with any hepatic or renal disease.
7. Patient with any neurological and musculoskeletal disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To determine if prophylactic intramuscular glycopyrrolate administration reduces the incidence and severity of hypotension associated with spinal anaesthesia in elderly patients. <br/ ><br>2. To determine the difference in proportion of cases who develop hypotension after spinal anaesthesia between two groups.Timepoint: 24 hrs
- Secondary Outcome Measures
Name Time Method 1. To determine the difference in hemodynamic variables (Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure) from baseline to different time intervals post the subarachnoid block between two groups. <br/ ><br>2. To determine the difference in total dose of rescue vasopressor used between study groups.Timepoint: 24hrs