Is Routine Use of Histopathological Examination Necessary After Cholecystectomy ?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,000
- 试验地点
- 6
- 主要终点
- The comparison of macroscopic and histopathologic examination of the cholecystectomy specimen with 1000 cases
研究概览
简要总结
Cholecystectomy has been made with benign conditions usually. The aim of this study is to compare the macroscopic evaluations of the cholecystectomy specimens with it's histopathological examinations.
详细描述
Cholecystectomy is one of the most frequently performed surgery in the world and often made with benign conditions. Routinely cholecystectomy specimens sent for histopathologic examination. The histopathologic examination of the cholecystectomy specimens are benign in most of the cases and the incidental malignancy of the gallbladder is 2-2.9% in the literature. The histopathologic evaluations of the gallbladder come with additional workload for pathology and surgery departments. Also there is additional cost for the patients. Because of that the idea of selective histopathologic examination has been raised.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subject has cholelithiasis
排除标准
- •Subject has acute cholecystitis
- •Subject has perforated gallbladder
- •Subject has malignancy
- •Subject has polyps in the gallbladder
- •Subject has increasing wall thickness of the gallbladder
- •Subject has malignancy in the preoperative ultrasonography in the gallbladder
- •Subject has pregnancy
结局指标
主要结局
The comparison of macroscopic and histopathologic examination of the cholecystectomy specimen with 1000 cases
时间窗: 15 days
The 1000 cholecystectomy specimens will be evaluated macroscopically by two experienced surgeons with a longitudinal incision to the gallbladder. The specimens will be grouped as benign, suspicious, malign according to the surgeon's decision. To confirm the surgeon's macroscopic evaluation, all of the specimens will be evaluated histopathologically. The results of macroscopic and histopathological examinations will be compared.
次要结局
未报告次要终点
研究者
Ufuk Oguz Idiz
M.D.
Sisli Hamidiye Etfal Training and Research Hospital