The full scope of oxytocinergic influences on the parental brain: Maternal defensiveness and grandparent-child interactions

Completed

Conditions: Adult-child interaction, behavioral and brain responses
Not applicable
10001474

Registration Number: NL-OMON41352

Lead Sponsor: niversiteit Leiden

Brief Summary: Trial is onging in other countries

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 10

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:
-Mothers: healthy female subjects, 25-40 years old
-Grandmothers: healthy female subjects, 50-65 years old
-Infants: healthy infants, 5-6 months old during the first laboratory visit

Exclusion Criteria

A potential subject who meets any of the following criteria during a telephone prescreening will be excluded from participation in this study:
-Breastfeeding
-Any known neurological, visual, and auditory impairment
-Use of medication (except oral contraceptives)
-Drug or alcohol abuse
-Psychiatric disorder
-Nasal disease or obstruction
-Smoking
-Pregnancy

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are a) the intensity of the mother*s<br /><br>defensive/protective responses during the ESP, b) the direction and magnitude<br /><br>of frontal EEG asymmetry and event-related potentials in response to images of<br /><br>their own infant in different priming contexts (social threat vs. neutral), c)<br /><br>observed caregiving sensitivity, d) salivary levels of oxytocin, and e)<br /><br>self-reported attachment representations. </p><br>

Secondary Outcome Measures