Influence of Different Zirconia Surface Treatments on Biofilm Formation

University of Basel1 site in 1 country16 target enrollmentJanuary 1, 2020

ConditionsSurface Finish

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Surface Finish
Sponsor: University of Basel
Enrollment: 16
Locations: 1
Primary Endpoint: Safranin Staining
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim is to test the influence of surface finish on biofilm formation on the transmucosal part of zirconia implants in an in vivo study. Sixteen test person will therefore receive an orthodontic apparatus containing the specimens with the respective surfaces and carry them for 2x 24h. The primary outcome is the spectormetrical quantification (OD value) of biofilm on the specimens that have been carried by the test person over 24h. Biofilm will be analysed using scanning electron microscopy.

Registry

clinicaltrials.gov

Start Date

January 1, 2020

End Date

August 1, 2020

Last Updated

5 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

University of Basel

Responsible Party

Principal Investigator

Nadja Rohr

Principal Investigator

University of Basel

Eligibility Criteria

Inclusion Criteria

•No systematic antibiotic therapy during the last 3 months
•Good oral health and compliance (PI and BI \<20%)
•No sign of parodontal disease or other inflammatory changes in the mouth
•Non-smoker

Exclusion Criteria

•Disease that requires antibiotic therapy
•Pressure marks due to the orthodontic apparatus that can not be eliminated
•Other unexpected complications that could be related to the orthodontic apparatus