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Comparison of Palonosetron with Palonosetron and Dexamethasone in avaoiding Post-Operative Nausea and Vomiting in Female Patients Undergoing Laparoscopy surgery

Not yet recruiting
Conditions
Calculus of gallbladder with acutecholecystitis,
Registration Number
CTRI/2019/09/021070
Lead Sponsor
SPS Hospitals
Brief Summary

Aim of the study is to compare the clinical efficacy of Palonosetron with Palonosetron and Dexamethsone in prevention of post-opertative nausea and vomiting in female patients undergoing laproscopic cholecystectomy. total 120 ASA grade 1 and 2 patients were enrolled.

Primary objective is to compare the incidence of post operative nausea and vomiting during first 24 hours and to compare the severity of nausea.

Secondary objective is to identify the need of anti emetic , number of complete responders and to observe the incidence of adverse effects of Palonosetron and Dexamethsone.

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
Female
Target Recruitment
120
Inclusion Criteria

Female Patients Laproscopic Cholecystectomy ASA grade 1 and 2.

Exclusion Criteria

History of DM Psychiatric disorder BMI more than 30kg/m2 Male Patients ASA grade 3 and 4.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of Post Operative Nausea and Vomiting24 hours
Secondary Outcome Measures
NameTimeMethod
Need of Rescue Anti-emetic24 hours
Adverse effect of Inj Palonosetronand Inj Dexamethasone

Trial Locations

Locations (1)

SPS Hospitals

🇮🇳

Ludhiana, PUNJAB, India

SPS Hospitals
🇮🇳Ludhiana, PUNJAB, India
Dr Aashima Jain
Principal investigator
9815271382
aashimajain11992@gmail.com

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