ltrasound-Guided regional Anaesthesia in Patients receiving Dressing Change After split-Skin grafting for Upper Limb burn Injuries: A Prospective Randomized Study

Phase 1

Completed

• Conditions: Acute Burn Pain; Anaesthesiology - Pain management

• Registration Number: ACTRN12617001054303
• Lead Sponsor: Cienwen Town

Brief Summary

nil

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-07-19
• Study Completion: 2020-10-19
• Last Update Posted: 29 March 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Patients aged >17 years
-Split Skin Grafting to their upper limbs
-ASA 1-3
-Patients remaining in hospital until change of dressing

Exclusion Criteria

-Patients with burns >20%
-Patients with significant burns requiring grafting to areas other than the upper limbs
-History of local anaesthetic allergy
-Contraindication to regional anaesthesia
-Severe respiratory disease
-Inability to give informed consent
-Physiological/neurological shoulder/nerve deficits
-Significant coagulopathy and anticoagulant treatment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The efficacy of regional anaesthesia for the treatment of pain associated with dressing change in patients suffering burn related injuries will be judged based on the 10 point numeric pain scale.[Primary time point will include data collection during the immediate dressing change phase- patient pain will be recorded immediately before, during and after the dressing change procedure. Then daily for 7 days post dressing change or until discharge if that occurs sooner. ];The efficacy of regional anaesthesia will be judged based on rescue analgesia and opioid equivalents. This data will be collected prospectively and through review of medical records.[Primary time point will include data collection covering the 24 hours before dressing change procedure, requirements during the procedure, and then daily requirements for 7 days post dressing change or until discharge if that occurs sooner. ]

Secondary Outcome Measures

Name	Time	Method
The efficacy of regional anaesthesia will be judged pre-operatively by a three point sensory and function motor scale. This scale is routinely utilised in regional anaesthesia assessment and has been employed across a variety of regional anaesthesia studies. It is a known method of assessment, though not a validated tool.[Assessment will take place 10 minutes, 20 minutes, and 30 minutes after the regional block has been placed and before the participants commence their dressing change procedure.];Patient functionality in terms of pain, self-efficacy and experience will be evaluated.[6 months post-procedure, patients will be followed up in the community setting via administration of 2 questionnaires (The Modified Brief Pain Inventory short form and EQ-5D-5L) and one semi-structured phone interview. ]