Phase-Specific Evaluation of Lung Mechanics and Ventilation Efficiency During Robotic Surgery: A Prospective Observational Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 145
- 试验地点
- 1
- 主要终点
- Ventilation Efficiency Index (VEI) change across robotic surgery phases
研究概览
简要总结
Robotic surgery requires pneumoperitoneum and specific surgical positioning such as steep Trendelenburg, reverse Trendelenburg, or supine positioning. These intraoperative conditions may lead to cranial displacement of the diaphragm, reduced lung compliance, and increased airway pressures, potentially impairing respiratory mechanics and gas exchange.
Previous studies have primarily evaluated respiratory mechanics during robotic surgery at single time points or within specific surgical procedures. However, dynamic changes occurring during critical phases of robotic surgery have rarely been evaluated prospectively.
This prospective observational cohort study aims to evaluate phase-specific changes in lung mechanics and ventilation efficiency during robotic surgery. Key parameters including mechanical power (MP), ventilation efficiency index (VEI), static compliance, and driving pressure will be analyzed across predefined intraoperative phases.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 years
- •Patients undergoing robotic surgery
- •General anesthesia with mechanical ventilation
- •Written informed consent
排除标准
- •Severe chronic pulmonary disease
- •Refusal to participate
- •Missing intraoperative ventilatory data
研究组 & 干预措施
Robotic Surgery
Adult patients undergoing robotic surgery under general anesthesia with mechanical ventilation. Intraoperative respiratory mechanics and gas exchange parameters will be prospectively recorded during predefined phases of robotic surgery (T0-T4). Parameters include ventilatory settings, airway pressures, arterial blood gas values, and calculated indices such as mechanical power, driving pressure, static compliance, and ventilation efficiency index. The study evaluates phase-specific changes in lung mechanics and ventilation efficiency during robotic surgical procedures.
干预措施: Intraoperative Mechanical Ventilation Monitoring (Other)
结局指标
主要结局
Ventilation Efficiency Index (VEI) change across robotic surgery phases
时间窗: Intraoperative (T0-T4)
Evaluation of VEI changes between predefined intraoperative phases.
次要结局
- Mechanical Power Change(intraoperative)
- Static Lung Compliance Change(intraoperative)
研究者
Betül Güven
Assos. Prof
Ankara City Hospital Bilkent