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Clinical Trials/NCT07467135
NCT07467135
Not yet recruiting
Not Applicable

Phase-Specific Evaluation of Lung Mechanics and Ventilation Efficiency During Robotic Surgery: A Prospective Observational Cohort Study

Ankara City Hospital Bilkent0 sites65 target enrollmentStarted: March 20, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
65
Primary Endpoint
Ventilation Efficiency Index (VEI) change across robotic surgery phases

Overview

Brief Summary

Robotic surgery requires pneumoperitoneum and specific surgical positioning such as steep Trendelenburg, reverse Trendelenburg, or supine positioning. These intraoperative conditions may lead to cranial displacement of the diaphragm, reduced lung compliance, and increased airway pressures, potentially impairing respiratory mechanics and gas exchange.

Previous studies have primarily evaluated respiratory mechanics during robotic surgery at single time points or within specific surgical procedures. However, dynamic changes occurring during critical phases of robotic surgery have rarely been evaluated prospectively.

This prospective observational cohort study aims to evaluate phase-specific changes in lung mechanics and ventilation efficiency during robotic surgery. Key parameters including mechanical power (MP), ventilation efficiency index (VEI), static compliance, and driving pressure will be analyzed across predefined intraoperative phases.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Age ≥ 18 years
  • Patients undergoing robotic surgery
  • General anesthesia with mechanical ventilation
  • Written informed consent

Exclusion Criteria

  • Severe chronic pulmonary disease
  • Refusal to participate
  • Missing intraoperative ventilatory data

Arms & Interventions

Robotic Surgery

Adult patients undergoing robotic surgery under general anesthesia with mechanical ventilation. Intraoperative respiratory mechanics and gas exchange parameters will be prospectively recorded during predefined phases of robotic surgery (T0-T4). Parameters include ventilatory settings, airway pressures, arterial blood gas values, and calculated indices such as mechanical power, driving pressure, static compliance, and ventilation efficiency index. The study evaluates phase-specific changes in lung mechanics and ventilation efficiency during robotic surgical procedures.

Intervention: Intraoperative Mechanical Ventilation Monitoring (Other)

Outcomes

Primary Outcomes

Ventilation Efficiency Index (VEI) change across robotic surgery phases

Time Frame: Intraoperative (T0-T4)

Evaluation of VEI changes between predefined intraoperative phases.

Secondary Outcomes

  • Mechanical Power Change(intraoperative)
  • Static Lung Compliance Change(intraoperative)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Betül Güven

Assos. Prof

Ankara City Hospital Bilkent

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