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Remote Monitoring of Diabetes in Pregnancy: a Feasibility Study

Not Applicable
Completed
Conditions
Gestational Diabetes
Interventions
Device: Telemonitoring
Other: Control
Registration Number
NCT01630759
Lead Sponsor
University of Ulster
Brief Summary

When women with diabetes become pregnant it is particularly important to control blood sugar levels to prevent complications. Women are advised to test their blood glucose levels seven times a day and to attend antenatal and diabetes clinics every 1-2 weeks throughout the pregnancy. For those living in rural areas in the North and West of Ireland getting to a hospital specialising in the management of diabetes and pregnancy on such a regular basis can be a challenge.

Telemonitoring provides a possible solution to this problem by allowing patients to monitor their vital signs at home and transmit the information via telephone to their healthcare provider. If women could be safely monitored remotely for every other appointment it would mean that they would only need to visit the hospital once a month on a routine basis but with the option of attending the hospital if the remote telemonitoring indicated that this were necessary.

The aim of this study is to assess the feasibility and the acceptability of using remote telemonitoring facilities between antenatal women with gestational diabetes and the diabetes team and the possibility of replacing alternate diabetic review clinics with remote telemonitoring. In addition this study will explore the feasibility of running a full randomised control trial of this topic.

Women will be asked to monitor their blood sugar levels seven times a day which is part of usual care. However those in the remote telemonitoring group will be asked to measure their blood sugar using a meter that can transmit the results via a telephone line and to transmit them weekly. They will also be asked to measure their blood pressure and weight weekly and to download these results weekly for a health care professional to review. These results will be reviewed on a weekly basis by a health care professional who will contact the patient if necessary to discuss the results. Women will be followed-up from the date of diagnosis through to delivery.

Both staff and patients will be asked to give their views on the safety and acceptability of remote telemonitoring through questionnaires, focus groups or interviews. The management decisions made on reviewing the intervention group in clinic and reviewing remote telemonitoring results will also be recorded. In order for remote telemonitoring to be a viable replacement for clinic review it must allow health care professionals to make comparable management decisions. Clinical data will be collected in order to provide descriptive statistics for those who take part and to ensure that this information could be collected in any future Randomised Control Trial (RCT) looking at this topic.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
50
Inclusion Criteria
  • Pregnant
  • Gestational Diabetes or IGT following an oral glucose tolerance test performed at the 24-28 week screening appointment
  • Able to use the telehealth equipment following training by staff from the company providing telehealth services
  • Have sufficient communication skills [hearing, speech & language] to be fully involved.
  • Willing to use one of the approved blood glucose meters for self monitoring of blood glucose, for the duration of the study.
Exclusion Criteria
  • Previously diagnosed Type 1 diabetes or Type 2 diabetes as evidenced by medical records.
  • Other diagnosed medical problems or medical therapy such as steroid therapy that would influence blood glucose control and to be decided by the endocrinologist prior to recruitment. Such exclusions to be noted by the endocrinologist or diabetes nurse specialist.
  • Previous gestational diabetes is not an exclusion criterion.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
TelemonitoringTelemonitoringThe telemonitoring group will receive usual care but be asked to download their blood sugar readings and take a blood pressure and weight measurement each week. This will be reviewed by their diabetes health care team to assess the possibility of replacing alternate anti-natal/diabetes clinics with telemonitoring review in a future study. Acceptability to staff and patients will be assessed through a questionnaire (patients only) and qualitative interviews.
Control groupControlControl group will consist of usual care and review at clinic.
Primary Outcome Measures
NameTimeMethod
Patient satisfactionAt 36-39 weeks gestation

The previously validated 'Telemedicine satisfaction and usefulness questionnaire' will be used to assess patient satisfaction with the telemonitoring service.

Qualitative interviews exploring the patient experience of telemonitoring will also be carried out and then analysed using the framework approach. An adapted version of this questionnaire looking specifically at the use of a blood glucose meter will be given to the control group.

Health care staff satisfactionAt completion of the study estimated to be January 2013

The professionals involved in caring for the women using remote telemonitoring technology in antenatal or diabetes clinics will be invited to take part in a focus group at each site. If it is not possible to arrange a time and place suitable for staff in order to hold a focus group it may be necessary to hold one to one structured interviews with staff. The questions used in the focus group will aim to assess the acceptability of telemonitoring to health care staff who use it.

Management decision comparisonAt weekly clinic or telemonitoring review from time recruited into study to delivery, estimated at an average of twelve weeks.

Weighted kappa will be used to meaure the level of agreement in between clinic and telemonitoring review management decisions (in excess of the amount of agreement that we would expected by chance). This will allow the determination of inter-rater, intra-rater and inter-institutional agreement between clinic and telemonitoring review management decisions.

Secondary Outcome Measures
NameTimeMethod
HbA1cMonthly for duration of participation in study, estimated at 2-3 months

HbA1c mmol/l and IFCC units

Mean fasting blood glucoseWeekly for duration of participation in study, estimated at 12 weeks

mmol/l plasma glucose

Blood pressureWeekly for duration of participation in study, estimated at 12 weeks

mmHg

Head circumferenceAt birth

centimeters

Gestational age at deliveryAt delivery

Gestational age in weeks at delivery

Type of deliveryAt delivery

Vaginal or Caesarean section

Pre-eclampsiaAt delivery

Presence or absence of any pre-eclampsia

Apgar scoreAt birth

Apgar score at one and five minutes (out of 10)

Admission to neonatal unitAt one day after birth

Whether the baby needed admission to the neonatal unit

Documented problems with pregnancyAt delivery

Presence of any documented problems during pregnancy

Weight of babyAt birth

Weight in kg

Respiratory distressAt one day after birth

Presence of any episodes of documented Respiratory distress in first 24 hours of life

JaundiceAt one day after birth

Presence of any jaundice in first 24 hours of life

Length of babyAt birth

centimeters

Neonatal hypoglycaemiaAt one day after birth

Presence of any documented episodes of neonatal hypoglycaemia in first 24 hours of life

Shoulder dystociaAt birth

Presence of any shoulder dystocia

MalformationsAt delivery

Any malformations at delivery

Post-prandial blood glucoseWeekly for duration of participation in study, estimated at 12 weeks

mmol/l plasma glcuose

MacrosomiaAt birth

Presence or absence of macrosomia

Average number of monitoring episodes per dayAt delivery

Average number of monitoring episodes per day

Number of downloads missedAt delivery

Number of downloads missed by those in the telemonitoring group

Trial Locations

Locations (2)

Letterkenny General Hospital

🇮🇪

Letterkenny, Donegal, Ireland

Altnagelvin Hospital

🇬🇧

Londonderry, United Kingdom

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