A Randomised Trial of Exercise Therapy for Parkinson’s Disease

Not Applicable

Completed

• Conditions: Parkinson’s disease; Neurological - Parkinson's disease; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12620001135909
• Lead Sponsor: a Trobe University

Brief Summary

Parkinson's patients received physiotherapy in either an outpatient clinic or at home and outcomes were assessed.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-10-30
• Study Completion: 2022-12-05
• Last Update Posted: 13 June 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

a. Parkinson’s disease
b. Modified Hoehn & Yahr stage 3 or less when tested ON.
c. Age 30-75 years
d. Sedentary lifestyle (low levels of aerobic physical activity, defined by the American College of Sports Medicine recommendation for older adults as just any level below recommended weekly amount of aerobic exercise).
e. Receiving a stable dopaminergic medication dose (levodopa and/or a dopamine agonist) for at least one month before the study, or else De-novo – not receiving PD medication

Exclusion Criteria

a) Judged unsafe to exercise by medical practitioner
b) Currently using beta-blockers
c) Currently using anti-psychotics
d) Unable to cycle, use a treadmill or perform stretching exercises due to neurological conditions or co-morbidities
e) Unable to fill out questionnaires due to poor vision or other reasons
f) Unable to independently transport self to the exercise venue
g) Unable to read
h) Psychiatric conditions or major depression
i) Mini Mental Status Examination (MMSE) score of less than 24
j) Contra-indications to aerobic exercise, such as diagnosed cardiac diseases (eg. unstable angina, heart block, arrhythmia’s, uncontrolled hypertension), poorly controlled diabetes

Study & Design

• Study Type: Interventional
• Study Design: Not specified