NCT04980911
Completed
Not Applicable
Iron Deficiency and Anemia in Cardiovascular Surgery
Centre Hospitalier Régional Metz-Thionville1 site in 1 country1,711 target enrollmentApril 12, 2021
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anemia
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
- Enrollment
- 1711
- Locations
- 1
- Primary Endpoint
- Number of transfusion
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Anemia and preoperative iron deficit in cardiac surgery are associated by an increased volume of transfusion and an increase in complications and/or mortality. Recent studies have shown that EPO and iron administration the days preceding the operation results in a reduction of perioperative transfusion for patients with preoperative anemia.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient with cardiac surgery
- •With iron deficiency with or without anemia
Exclusion Criteria
- •Anemia without iron deficiency
- •Iron overload
- •Jehovah's witnesses
- •Endocarditis
- •Treating neoplasia
- •Uncontrolled hypertension
- •With infection
- •Alfa-epoetin hypersensitivity
- •Hypersensitivity of hamster's protein
- •Erythroblastopenia induced by erythropoietin
Outcomes
Primary Outcomes
Number of transfusion
Time Frame: Day 7
number of perioperative and post-operative transfusion
Secondary Outcomes
- Number of post operative complications(Day 7)
- Percentage of death(Day 7)
Study Sites (1)
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