Comparison of thromboelastometry with classical coagulation tests in cardiac surgery

Completed

• Conditions: Coagulation; hemostasis; 10007593

• Registration Number: NL-OMON33435
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 23

Inclusion Criteria

Patients undergoing elective cardiothoracic surgery
Age 18-90 years
Preoperative hemoglobin of > 5.5 mmol/l
Informed consent

Exclusion Criteria

Re-operations and emergency operations
Use of erythropoietin
Patients receiving blood transfusions < 1 month before surgery
Hepatic or renal failure

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Level of comparison of ROTEM INTEM clotting time and aPTT (classical<br /><br>coagulation test)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Level of comparison of FIBTEM and Clauss test for fibrinogen.<br /><br>Demographic variables: Age, gender, length, body weight, preoperative and<br /><br>postoperative hematocrit, hemoglobin, leukocyte count.<br /><br>Surgical characteristics: Surgery time, clamp time, CPB time.<br /><br>Medicine use: use of drugs that influence coagulation<br /><br>Administration of blood products and fluid, urine production<br /><br>Comparison of treatment decision based on classical coagulation parameters and<br /><br>ROTEM analysis.</p><br>