The Effects of Jerusalem Artichoke and Fermented Soybean Powder Mixture Supplementation on Glucose Control
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- Blood glucose level by 2-h oral glucose tolerance tests (OGTTs)
研究概览
简要总结
The purpose of this randomized, double-blind, placebo-controlled study was to determine whether jerusalem artichoke and fermented soybeans powder mixture is effective in the control of blood glucose level in subjects with prediabetes or newly diagnosed type 2 diabetes.
详细描述
The objective of this clinical study was to evaluate the effect of jerusalem artichoke and fermented soybean powder mixture supplementation on blood glucose. A randomized, double-blinded, placebo-controlled study was conducted on 60 subjects with impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or newly diagnosed type 2 diabetes. The subjects were randomly assigned to either a group ingesting 40 g jerusalem artichoke and fermented soybean powder mixture supplementation daily or a placebo group for 12-week. We assessed fasting and postprandial levels of glucose.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All subjects were with prediabetes (IFG or IGT) or newly diagnosed type 2 DM (T2DM) no taking medicine. IFG was defined as fasting glucose between 100 and 125 mg/dL and IGT was defined as 2-h OGTTs glucose levels 140-199 mg/dL. Newly diagnosed type 2 diabetes was defined as fasting glucose ≥126 mg/dL or 2-h OGTTs level ≥ 200 mg/dL.
排除标准
- •glucose lowering medications or insulin injections;
- •abnormal liver or renal function;
- •chronic stomach and intestines disease;
- •chronic alcoholism;
- •pregnancy or intending to become pregnant during time of study.
- •complications;
- •an occupation that could be dangerous if hypoglycemia should occur.
研究组 & 干预措施
Test group
jerusalem artichoke and fermented soybeans powder mixture supplementation
干预措施: jerusalem artichoke and fermented soybeans powder mixture (Dietary Supplement)
Placebo group
placebo supplementation
干预措施: placebo (Dietary Supplement)
结局指标
主要结局
Blood glucose level by 2-h oral glucose tolerance tests (OGTTs)
时间窗: 12 week
次要结局
未报告次要终点