The effect of iodine excess on thyroid function of women undergoing infertility assessment (Hysterosalpingram) using Lipiodol dye and the potential impact on their babies

Not Applicable

Completed

• Conditions: Infertility; Subclinical hypothyroidism; Hashimotos thyroiditis; Reproductive Health and Childbirth - Fetal medicine and complications of pregnancy; Reproductive Health and Childbirth - Complications of newborn; Metabolic and Endocrine - Thyroid disease; Reproductive Health and Childbirth - Fertility including in vitro fertilisation

• Registration Number: ACTRN12620000738921
• Lead Sponsor: iggins Institute,University of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-07-14
• Study Completion: 2022-02-14
• Last Update Posted: 10 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 196

Inclusion Criteria

Any woman of the reproductive age group who is going for a Lipiodol HSG if they have

1. Normal thyroid function demonstrated by normal free T4

2. Subjects with subclinical hypothyroidism (defined as a TSH >97th percentile or 2.5 IU/L and normal Free T4 levels) are included.

Exclusion Criteria

1. Subject taking medication known to affect thyroid function or iodine metabolism (e.g. Lithium, amiodarone etc.)
2. Active thyroid disease including hyperthyroidism, hypothyroidism, thyroid cancer and benign goitre.
3. A previous radiological dye study within the last 3months for aqueous dyes and6months for fat soluble dyes as this will affect urine iodine interpretation.

Study & Design

• Study Type: Observational
• Study Design: Not specified