Levels of Circulating T Cells Expressing VLA-1 Collagen Receptors

Completed

• Conditions: Ischemic Heart Disease

• Registration Number: NCT00708838
• Lead Sponsor: Sheba Medical Center

Brief Summary

The examination of the percentage of peripheral T cells carrying VLA-1 in ischemic heart disease patients. The hypothesis is that the percentage levels of cells carrying this integrin rise according to the severity of the ischemic heart disease.

Detailed Description

Atherosclerosis is considered an inflammatory disease in which lymphocytes have an important role. The study was disigned to find out the changes in T cell levels carrying VLA-1 involvement in this process.

Study Timeline

• Study Start: 2002-01
• Primary Completion: 2006-01
• Study Completion: 2007-02
• Status Verified: 2008-07
• Study First Submitted: 2008-07-01
• Study First Submitted QC: 2008-07-01
• Last Update Submitted: 2008-07-01
• Study First Posted: 2008-07-02
• Last Update Posted: 2008-07-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 151

Inclusion Criteria

• clinical diagnosis of acute MI for group 1
• clinical diagnosis of ACSl for group 2
• clinical diagnosis of Chronic Heart Disease for groups 3 and 4
• Chest pain but normal heart scan for group 5

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The differance in percentage of T cells in the 5 different groups involved.	2002-2006