Post hoc analysis of web-based survey (ref. UMIN000048497) on emotional blunting in Japanese patients with Major Depressive Disorder

Not Applicable

• Conditions: Major depressive disorder (MDD)

• Registration Number: JPRN-UMIN000051822
• Lead Sponsor: Takeda Pharmaceutical Company Limited.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-08-09
• Study Start: 2023-08-07
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 3376

Inclusion Criteria

Not provided

Exclusion Criteria

The preliminary web-based questionnaire ask whether any of the following conditions are met, and those who meet the conditions are not eligible for the survey. (1) Those who have been diagnosed with bipolar disorder. (2) Those not currently taking antidepressants

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation of ODQ/ODQ sub-domain (General reduction (GR), Positive reduction (PR), Emotional detachment (ED), Not caring (NC), Antidepressant as cause (AC)) scores with Workand Social Adjustment Scale (WSAS)/WSAS sub-item scores and PHQ-9/PHQ-9 sub-item scores

Secondary Outcome Measures

Name	Time	Method
Secondary Endpoint: - Relationship between patient background factors and with/without gap between the degree of subjective EB symptoms and ODQ scores Exploratory Endpoint: - Contribution of ODQ subdomains to WSAS and PHQ-9 after adjusting for interrelationships among WSAS, PHQ-9 and ODQ - Relationship between expressions used by patients and MDD -related characteristics (ODQ, PHQ-9 and subjective EB scores)