Prolonged ENoxapariN in primarY percutaneous coronary intervention compared WIth Standard-of-carE therapy: Feasibility study (PENNYWISE Feasibility) - PENNYWISE Feasibility Trial

Sheffield Teaching Hospitals NHS Foundation Trust0 个研究点目标入组 100 人开始时间: 2018年6月30日最近更新: 2020年7月13日

试验速览

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•Confirmation of the diagnosis of STEMI by the clinical team on the basis of history and ECG changes
•Intention to proceed with PPCI
•Treated with opiates for analgesia
•Feasibility to obtain informed verbal consent pre PPCI
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 20
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 80

•1.Active bleeding that cannot be controlled by local measures
•2.Pregnant patients
•3.Patients with end-stage renal failure requiring renal replacement therapy
•4.Patients with cardiogenic shock
•5.Known thrombocytopenia (Platelet count < 100,000/µL)
•6.Known history of intracranial haemorrhage
•7.Known current treatment with oral anticoagulants
•8.Known history of major surgery or trauma or history of GI/GU haemorrhage within the last month
•9.Known intracranial malignancy or aneurysm
•10.Known allergy to enoxaparin
•11.Known hypersensitivity to benzylalcohol
•12.Patients with known acute bacterial endocarditis
•13.Known active gastric or duodenal ulceration
•14.Inability to easily understand verbal information given in English for any reason
•15.Inability to give informed consent due to either temporary or permanent mental incapacity
•16.Current participation, or participation within the last month, in an interventional clinical trial.

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