A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy

Not Applicable

Active, not recruiting

• Conditions: Pain
• Interventions: Other: Nerve block

• Registration Number: NCT06553495
• Lead Sponsor: Jie Chen

Brief Summary

This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for postoperative pain management of liver surgery.

Detailed Description

This study was a prospective, double-blind, randomized controlled trial. Patients who were eligible for laparoscopic partial liver resection in our center were included, with intertransverse nerve block as the experimental group and paravertebral nerve block as the control group. Through the analysis of postoperative pain score 30min to 24h, the number of effective analgesic pump compressions within 24h, the amount of analgesic drugs used, complications and other data, To evaluate the efficacy and safety of intertransverse nerve block in patients undergoing laparoscopic partial liver resection.

Study Timeline

• Status Verified: 2024-08
• Study Start: 2024-08-01
• Study First Submitted: 2024-08-12
• Study First Submitted QC: 2024-08-12
• Last Update Submitted: 2024-08-12
• Study First Posted: 2024-08-14
• Last Update Posted: 2024-08-14
• Primary Completion: 2026-11-30
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1:

1.18-80 years old adult, BMI<27.9kg/m2

2: 2. American Society of Anesthesiologists ASA Grade I-III

3: 3. Patients with laparoscopic partial liver resection such as liver tumors

4: 4. Willing to participate in this study and sign the informed consent form

Exclusion Criteria

1. 1. The patient or family member refuses to sign the informed consent form
2. 2. Blood coagulation dysfunction, local infection
3. 3. Those who have communication, communication disorders or mental abnormalities
4. 4. Patients with severe heart, pulmonary and renal insufficiency or patients with central system diseases
5. 5. For any reason, it cannot be matched with the study or the researcher believes that it is not appropriate to be included in this experiment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
intertransverse nerve block	Nerve block	To study the analgesic effect of intertransverse nerve block after endoscopic hepatectomy
paravertebral nerve block	Nerve block	To study the analgesic effect of paravertebral nerve block after endoscopic hepatectomy

Primary Outcome Measures

Name	Time	Method
The number of effective compressions of the analgesic pump within 24 hours after surgery	Within 24 hours after the operation

Trial Locations

Locations (1)

The Second Affiliated Hospital Of Chongqing Medical University; 🇨🇳 Chongqing, Chongqing, China