Assessment of the efficacy of Yashtimadhvadi Pratisarna (Toothpaste) in reducing Dantaharsha (Dentinal Hypersensitivity)-A Clinical and Scanning Electron Microscopic Study
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Reduction in dentinal hypersensitivity (Dantaharsha) as measured by Visual Analog Scale (VAS) scores after application of Yashtimadhwadi Pratisarana.
研究概览
简要总结
Dantaharsha (Dentinal Hypersensitivity) is a common dental complaint characterized by sharp pain in response to thermal, chemical, or tactile stimuli due to exposed dentinal tubules. The present clinical study aims to evaluate the efficacy of Yashtimadhwadi Pratisarana (Ayurvedic toothpaste prepared from Yashtimadhu-based formulation) in reducing dentinal hypersensitivity. Eligible participants will be randomly allocated to receive the intervention for 4 weeks, with assessment of pain reduction using the Visual Analog Scale (VAS) at baseline and post-intervention. The study also includes evaluation of changes in dentinal tubule occlusion through clinical examination (and Scanning Electron Microscopy if applicable). The trial is designed as a single-center, prospective clinical study conducted in the Department of Shalakyatantra, GOVT.AYURVED COLLEGE Nagpur, India.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having dentinal hypersensitivity at least in 2 teeth, having minimum 16 natural teeth free of large restoration or prosthetic crown, at least two teeth showing painful response using dental explorer.
排除标准
- •Teeth with severe caries, faulty restoration, prosthetic crown, chipping, fracture, symptoms of pulpal damage Participants who has taken long term analgesic therapy within 30 days before the start of the study Participants who have undergone any treatment for dentinal hypersensitivity in past 3 months Participants with ongoing orthodontic therapy Participants with history or presence kidney disorder, kidney stones, eating disorders, uncontrolled gastro-oesophageal reflux disease, excessive exposure to acids or any other systemic condition that predisposes to dentinal hypersensitivity Severe Periodontal disease characterized by extensive tooth mobility and or extensive alveolar bone loss involving 10 or more teeth Women who are pregnant or lactating.
结局指标
主要结局
Reduction in dentinal hypersensitivity (Dantaharsha) as measured by Visual Analog Scale (VAS) scores after application of Yashtimadhwadi Pratisarana.
时间窗: At baseline and after 4 weeks
Evaluation of changes in clinical symptoms (cold, sweet, sour stimuli response)
时间窗: At baseline and after 4 weeks
次要结局
- Evaluation of dentinal tubule occlusion through SEM analysis before and after intervention(Baseline (Day 0) and after completion of intervention (Week 4).)
研究者
DR SARIKA PALVE
Bhausaheb Mulak Ayurved College And RH Butibori Nagpur