MedPath

Evaluation of a Medical Food for Chronic Wounds

Phase 3
Completed
Conditions
Foot Ulcer, Diabetic
Interventions
Other: Medical Food
Other: Drink mix calorically similar to experimental product
Registration Number
NCT00711217
Lead Sponsor
Abbott Nutrition
Brief Summary

The study objective is to compare outcomes in subjects with a diabetic foot ulcer after 16 weeks of consuming a medical food versus a calorically similar control drink.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
271
Inclusion Criteria
  • non-pregnant
  • diabetic
  • neuropathic foot ulcer
  • ABI> 0.7
Exclusion Criteria
  • uncontrolled DM
  • collagen vascular disease or autoimmune disease
  • wound infection; recent therapies with steroids
  • growth factor or bioengineered tissue
  • radiation therapy
  • treatment with antibiotics within 1 week, Charcot's arthropathy of the foot
  • active malignancy
  • renal function impairment
  • liver failure
  • planned surgery
  • myocardial infarction within 3 months
  • malnutrition
  • substance abuse
  • taking conflicting oral nutritional supplements

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
#1 Medical foodMedical Food-
#2 ControlDrink mix calorically similar to experimental product-
Primary Outcome Measures
NameTimeMethod
Wound healing16 weeks
Secondary Outcome Measures
NameTimeMethod
QOL16 weeks
Wound healing measures16 weeks
Incidence of complications16 weeks
Clinical outcome data16 weeks

Trial Locations

Locations (51)

Foot and Ankle Clinic

🇺🇸

Los Angeles, California, United States

Beth Israel Deaconess Medical Center, Harvard University

🇺🇸

Boston, Massachusetts, United States

American Center for Clinical Trials

🇺🇸

Southfield, Michigan, United States

St. Vincent Charity Hospital, Wound Care Center

🇺🇸

Cleveland, Ohio, United States

Carlisle Regional Medical Center, Advanced Wound Healing Center

🇺🇸

Carlisle, Pennsylvania, United States

Limb Salvage Centre

🇺🇸

Dallas, Texas, United States

Diabetic Foot Clinic, King's College Hospital

🇬🇧

London, United Kingdom

Centro de Diagnostico y Tratamiento Francisco Diaz

🇪🇸

Madrid, Spain

Trinity Mother Frances Hospitals and Clinics

🇺🇸

Tyler, Texas, United States

Advance Foot & Ankle Center

🇺🇸

Las Vegas, Nevada, United States

Robert Wunderlich, DPM, P.A.

🇺🇸

San Antonio, Texas, United States

University of Texas Health Science Center at San Antonio

🇺🇸

San Antonio, Texas, United States

Endeavor Clinical Trials, PA

🇺🇸

San Antonio, Texas, United States

Diabetic Foot and Wound Center

🇺🇸

Denver, Colorado, United States

Therapeutics Clinical Research

🇺🇸

San Diego, California, United States

Southern Arizona VA Health Care System

🇺🇸

Tucson, Arizona, United States

University of Alabama

🇺🇸

Birmingham, Alabama, United States

Foot and Ankle Specialist

🇺🇸

Brawley, California, United States

Central Coast Foot and Ankle

🇺🇸

Freedom, California, United States

Biomedical Research and Educational Foundation of Southern Arizona VA Health Care System

🇺🇸

Tucson, Arizona, United States

Center for Clinical Research, Inc

🇺🇸

Castro Valley, California, United States

Advanced Clinical Research

🇺🇸

San Jose, California, United States

California School of Podiatric Medicine at Samuel Merritt University

🇺🇸

Oakland, California, United States

McHugh & Associates

🇺🇸

Watertown, Connecticut, United States

Pacific Wound Center

🇺🇸

Stockton, California, United States

Doctor's Research Network

🇺🇸

Miami, Florida, United States

SCORE Physician Alliance

🇺🇸

St. Petersburg, Florida, United States

Aiyan Diabetes Center

🇺🇸

Evans, Georgia, United States

Rosalind Franklin University, Center for Lower Extremity Ambulatory Research

🇺🇸

North Chicago, Illinois, United States

South Florida Wound Care Group

🇺🇸

Tamarac, Florida, United States

Ankle and Foot Associates

🇺🇸

Temple Terrace, Florida, United States

Chesapeake Research Group

🇺🇸

Pasadena, Maryland, United States

Christus Schumpert Wound Care Center & Hyperbaric Center

🇺🇸

Shreveport, Louisiana, United States

Foot Care, Endovascular and Vascular Services Boston University School of Medicine

🇺🇸

Boston, Massachusetts, United States

Gerard J. Furst, DPM, PLLC

🇺🇸

Port Jefferson Station, New York, United States

Foot Healthcare Associates

🇺🇸

Southfield, Michigan, United States

ProMedica Health Systems

🇺🇸

Toledo, Ohio, United States

Armstrong County Wound Healing Center

🇺🇸

Kittanning, Pennsylvania, United States

Temple University School of Podiatric Medicine

🇺🇸

Philadelphia, Pennsylvania, United States

The Wound Institute and Research Center

🇺🇸

Dunmore, Pennsylvania, United States

Blair Medical Associates, Inc.

🇺🇸

Altoona, Pennsylvania, United States

Health Concepts

🇺🇸

Rapid City, South Dakota, United States

Complete Family Foot Care

🇺🇸

McAllen, Texas, United States

Clinica de Podologia, Ciudad Universitaria

🇪🇸

Madrid, Spain

Chang Gung Memorial Hospital

🇨🇳

Taipei, Taiwan

Manchester Diabetes Centre

🇬🇧

Manchester, United Kingdom

Precision Foot and Ankle Centers - Torrance

🇺🇸

Torrance, California, United States

Akron General Medical Center, The Wound Care Center

🇺🇸

Akron, Ohio, United States

VA Medical Center

🇺🇸

Reno, Nevada, United States

Garrett Noguchi, DPM, P.A.

🇺🇸

Honolulu, Hawaii, United States

Amputation Prevention Center Broadlawns Medical Center

🇺🇸

Des Moines, Iowa, United States

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