A Comparative Clinical study on Erandathi Kwatha with Vaitarana vasti & Modern treatment regime in the management of Amavata(Rheumatoid arthritis) with special reference to Gut microbiota

Rheumatoid arthritis is the most common chronic, immune -inflammatory systemic disease. In india the prevalence of RA is 0.65% -0.75% according to API. Although the etiology and pathogenesis of RA is not clear but its presumed that autoimmunity plays a significant role in the genesis of disease, Chronicity and progression of RA. The conventional medical management is always challenged by the poor response, adverse effects, invasive complications. in this study, will evaluate the importance of anti-rheumatic drug induced host microbiota modulations and possible probiotics that can generate eubiosis. The present clinical study aim to assess clinically the efficacy of Erandathi Kwatha with Vaitharana vasti and Modern treatment regime in the management of Amavata(RA) with special reference to Gut microbiota. There will be 3 month duration with monthly follow up with medication. Assessment will be done on the basis of prepared proforma for subjective and objective parameters.