Seven days a week postoperative radiotherapy versus postoperative radiochemotherapy in cancer of the oral cavity or oropharynx

Completed

• Conditions: Squamous-cell cancer of the oral cavity or oropharynx; Cancer; Malignant neoplasm of oropharynx

• Registration Number: ISRCTN65457367
• Lead Sponsor: Polish Ministry of Science and Higher Education (Poland)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-08-31
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 270

Inclusion Criteria

1. Squamous-cell cancer of the oral cavity or oropharynx
2. Age at least 18 years
3. A written informed consent for participation in a trial
4. Macroscopically complete major surgery
5. Good performance status (ZUBROD 0-1)
6. White-cell count of at least 3500 per cubic millimeter
7. Platelet count of at least 100,000 per cubic millimeter
8. Creatinine clearence of more than 50 ml per minute
9. Aminotransferase and bilirubin values below twice the normal upper limit

Exclusion Criteria

1. Patients after reconstructive surgery with free-style flaps
2. Patients with stage pT1N0 disease
3. History of invasive cancer (except for nonmelanoma skin cancer)
4. Prior treatment
5. Distant metastases
6. For female participants, pregnant

Study & Design

• Study Type: Interventional
• Study Design: Not specified