The effect of an anti-inflammatory dietary program compared to standard healthy eating education on clinical and biochemical outcomes of knee osteoarthritis: The FEAST (eFfect of an Anti-inflammatory diet for knee oSTeoarthritis) randomised controlled trial

a Trobe University0 个研究点目标入组 144 人开始时间: 2022年3月18日最近更新: 2024年5月13日

适应症

试验速览

暂无简介。

•Aged 45-85 years
•Knee pain on most days of the past month
•Knee pain for at least 3 months
•Average knee pain during weight-bearing activities in the last week of at least 4/10 on numerical rating scale
•No morning knee stiffness, or morning stiffness that lasts <30mins in the past week
•Be willing to attend 3-4 phone consults and in-person 12- and 26-week follow-up

•Another reason than OA for knee symptoms (e.g., tumour, fibromyalgia)
•Planning to have knee surgery in next six months
•Already strictly following an anti-inflammatory diet (e.g., low carbohydrate, high-fat, paleo, Mediterranean)
•Following a habitual diet that excludes animal products (e.g., Vegan diet)
•Unable to follow anti-inflammatory diet (e.g., medically contraindicated, history of food allergy/hypersensitivity, family reasons)
•Contraindications for DEXA scans (e.g., pregnant or breastfeeding (or planning pregnancy in next 6 months), >200kg body weight (due to DEXA limits))
•>5kg weight fluctuation in past three months (i.e., unstable weight)
•Unable to understand written and spoken English
•Knee injection, injury or surgery in the past 3 months
•A diagnosed psychiatric disorder (excluding anxiety and depression)
•History of eating disorder or bariatric surgery
•Taking the following diabetic medication that affects blood sugar levels (i.e., insulin, SGLT 2 inhibitors, sulfonylureas) to mitigate the risk of hypoglycaemia/ketoacidosis
•Had all eligible knee joints replaced by arthroplasty

发起方

a Trobe University