Sildenafil citrate for the treatment of asymmetrical intrauterine growth restriction: A randomized controlled trial

Not Applicable

Recruiting

• Conditions: Pregnancy and Childbirth; Intrauterine growth restriction

• Registration Number: PACTR201705002278236
• Lead Sponsor: Ain Shams university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-05-08
• Last Update Posted: 2023-05-29

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

1.Pregnant Women diagnosed as IUGR.
2.Patients aged between 20¿40 years old.
3.Consenting to participate.

Exclusion Criteria

1.Severe preeclampsia with a diastolic blood pressure ¿ 110 mmHg on two occasions or systolic blood pressure ¿ 160 mmHg on two occasions and that, together with significant proteinuria (at least 1g/litre).
2.Fetus with reversed UA end diastolic flow.
3.Fetus diagnosed to have any congenital anomalies.
4.Diabetes mellitus with pregnancy.
5.Any contraindication for conservative management of IUGR as non-reassuring non-stress test (NST).
6.Patients with contraindication for the drugs given as gastric or duodenal ulcer, bleeding tendency and severe hypotension.
7.Smokers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified