A multicenter randomized controlled study to evaluate the efficacy of a 24-week multidomain intervention via face-to-face and video communication platforms in mild cognitive impairment

Inha University Hospital0 个研究点目标入组 300 人开始时间: 待定最近更新: 2021年10月5日

适应症

试验速览

暂无简介。

•60 to 79 years of age
•- Having at least one modifiable dementia risk factor
•- Complaints of cognitive decline by a participant or informant
•- A performance score that is lower than 1.0 standard deviations below the age-, and education-adjusted normative means for one or more of
•the delayed recall, naming, visuoconstruction, attention, and executive function tests
•- MMSE Z score = - 1.5
•- Independent activities of daily living
•- Being able to use the tablet PC through education, or having a person who can help a participant use the tablet PC.
•- Having a reliable informant who could provide investigators with the requested information
•- Provide written informed consent

•- Major psychiatric illness such as major depressive disorders
•- Dementia
•- Other neurodegenerative disease (e.g., Parkinson’s disease)
•- Malignancy within 5 years
•- Cardiac stent or revascularization within 1 year
•- Serious or unstable symptomatic cardiovascular disease
•- Other serious or unstable medical disease such as acute or severe asthma, active gastric ulcer, severe liver disease, or severe renal disease
•- Severe loss of vision, hearing, or communicative disability
•- Any conditions preventing cooperation as judged by the study physician
•- Significant laboratory abnormality that may result in cognitive impairment
•- Illiteracy
•- Unable to participate in exercise program safely
•- Coincident participation in any other intervention trial

发起方