South Korean study to prevent cognitive impairment and protect brain health through multidomain interventions via face-to-face and video communication platforms in mild cognitive impairment
- Conditions
- Mental and behavioural disorders
- Registration Number
- KCT0006592
- Lead Sponsor
- Inha University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 300
60 to 79 years of age
- Having at least one modifiable dementia risk factor
- Complaints of cognitive decline by a participant or informant
- A performance score that is lower than 1.0 standard deviations below the age-, and education-adjusted normative means for one or more of
the delayed recall, naming, visuoconstruction, attention, and executive function tests
- MMSE Z score = - 1.5
- Independent activities of daily living
- Being able to use the tablet PC through education, or having a person who can help a participant use the tablet PC.
- Having a reliable informant who could provide investigators with the requested information
- Provide written informed consent
- Major psychiatric illness such as major depressive disorders
- Dementia
- Other neurodegenerative disease (e.g., Parkinson’s disease)
- Malignancy within 5 years
- Cardiac stent or revascularization within 1 year
- Serious or unstable symptomatic cardiovascular disease
- Other serious or unstable medical disease such as acute or severe asthma, active gastric ulcer, severe liver disease, or severe renal disease
- Severe loss of vision, hearing, or communicative disability
- Any conditions preventing cooperation as judged by the study physician
- Significant laboratory abnormality that may result in cognitive impairment
- Illiteracy
- Unable to participate in exercise program safely
- Coincident participation in any other intervention trial
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method total scale index score of Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)
- Secondary Outcome Measures
Name Time Method Mini-Mental State Examination;Clinical Dementia Rating scale-Sum of Boxes ;Prospective and Retrospective Memory Questionnaire ;Geriatric Depression Scale-15 items ;Quality of life-Alzheimer‘s disease ;Bayer Activities of Daily Living ;Nutrition Quotient for elderly;Mini Nutritional Assessment ;Short Physical Performance Battery ;Pittsburgh Sleep Quality Index;Self Determination Index