ACTRN12615000518561已完成未知
Is the increase in permeability of the gut found in women with Crohn’s disease accompainied by greater absorption of bacterial endotoxin than in healthy women?
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20 Years 至 60 Years（—）
- 性别
- Female
入选标准
- •for Crohn's disease group
- •- Diagnosis of Crohn’s disease at least 6 months prior to the study
- •- either being in remission or having mild and moderate disease activity as assessed by the Harvey-Bradshaw Index (HBI) (remission: HBI <5, moderate disease activity: HBI 5-8, mild disease activity: HBI 8-16)
排除标准
- •- Have any dietary excesses or particularities e.g. food allergies
- •- Drink more than one alcoholic standard drink per day (or more than seven alcoholic standard drinks per week)
- •- Are pregnant or lactating
- •- Are taking vitamin/ mineral supplements
- •- Have a history of diabetes, renal (kidney) disorders or cancer
- •- Have an aversion to venepuncture, difficult veins, a history of bleeding disorders or on anticoagulant therapy
- •- recent consumption of foods containing lactulose or mannitol
- •additional exclusion criteria for healthy volunteers:
- •- Have a medical or family history of Crohn’s disease, ulcerative colitis or irritable bowel disease
- •- Have a recent history of abdominal pain, nausea, vomiting, diarrhoea, passage of blood and mucus in stool
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