NCT02923622Unknown不适用
Efficacy and Safety Evaluation of Traditional Chinese Medicine in the Treatment of Advanced Colorectal Cancer
Xiyuan Hospital of China Academy of Chinese Medical Sciences1 个研究点 分布在 1 个国家目标入组 384 人开始时间: 2016年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 384
- 试验地点
- 1
- 主要终点
- Overall survival
研究概览
简要总结
Although patients of colorectal cancer use Traditional Chinese Medicine (TCM) herbal therapy extensively in China, no strong evidence exists to demonstrate the safety and survival outcomes of TCM herbal therapy combined with conventional western medicine for treatment of this disease. The purpose of this multi-center perspective cohort study is to evaluate the relationship between TCM herbal therapy and survival outcomes in patients with advanced colorectal cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •histologically confirmed adenocarcinoma of the colon or rectum
- •TNM classification of stage IV disease according to American Joint Committee on Cancer
- •Between 18 and 80 years old
- •Progression or inability undergone conventional chemotherapy (Conventional chemotherapy regimen containing fluorouracil, oxaliplatin, irinotecan based chemotherapy, and all the above regimen should be used before)
- •Expected survival time is over 3 months
- •Signed informed consent
排除标准
- •serious non-malignant diseases such as heart, renal, and hepatic illnesses
- •the presence of other types of malignancies
- •The patients can not take medicine for intestinal obstruction
结局指标
主要结局
Overall survival
时间窗: 3 years
次要结局
- Progress free survival(3 years)
- Quality of life as assessed by FACT-C v4.0(3 years)
- Tumor control rate(3 years)
- TCM syndrome score(3 years)
- Number of participants with treatment-related adverse events as assessed by Chinese version of CTCAE v4.0(3 years)
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Treatment and Prevention of Traditional Chinese Medicines (TCMs) on COVID-19 InfectionPneumonia Caused by Human Coronavirus (Disorder)NCT04251871Beijing 302 Hospital150
已完成
不适用
A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth DiseaseHand, Foot and Mouth DiseaseNCT01182532The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine3,000
招募中
1 期
Clinical evaluation of traditional Chinese medicine on moderate active ulcerative colitis: a multi-center, randomized, double-blind, controlled trialITMCTR1900002336Dongfang Hospital of Beijing University of Chinese Medicine
尚未招募
1 期
Clinical evaluation of traditional Chinese medicine foot bath combined with antibiotics in the treatment of children with bacterial pneumoniaITMCTR2200006510The First Affiliated Hospital of Henan University of Chinese Medicine
招募中
4 期
Clinical evaluation of traditional Chinese medicine on mild active ulcerative colitis: a multi-center, randomized, double-blind, controlled trialITMCTR1900002335Jiangsu Province Hospital of Chinese Medicine