A prospective study of prophylactic effect of amiodarone on reperfusion ventricular fibrillation in cardiac surgical patients with ventricular hypertrophy.
Not Applicable
Recruiting
- Conditions
- Patients with ventricular hypertrophy undergoing elective cardiac surgery
- Registration Number
- JPRN-UMIN000010064
- Lead Sponsor
- Saitama cardiovascular and respiratory center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with ejection fraction of less than 40%, bundle branch block, QT prolongation,atrial fibrillation, pacemaker use, coronary artery disease. Patients with liver dysfunction, thyroid dysfunction, interstitial pneumonitis. Patients with renal dysfunction with creatinine >1.5mg/dl or creatinine clearance < 30ml/min, or hemodialysis treatment. Patients allergic to amiodarone or lidocaine.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence rate of reperfusion ventricular fibrillation after release of aortic cross clamp.
- Secondary Outcome Measures
Name Time Method The use of direct current shock,energy of direct current shock. The incidence rate of intraoperative and postoperative pacemaker use,postoperative arterial fibrillation. The incidence rate of postoperative pulmonary, thyroidal, and hepatic dysfunction. Ventilator time, intensive care unit stay, hospital stay, 30 day mortality. Laboratory data. perioperative hemodynamic data.