Real Life Effectiveness in Patients With Not Optimally Controlled Asthma

Phase 4

Completed

• Conditions: Asthma
• Interventions: Drug: Seretide

• Registration Number: NCT01647646
• Lead Sponsor: Far Eastern Memorial Hospital

Brief Summary

In real life, the investigators will be using different strategies including SMART therapy or other ICS/LABA (medium and high dose) therapy and measure the efficacy for asthma control.

Detailed Description

1. All not-well controlled asthma patients would include the study.

2. We will compare three ways of asthma control including SMART, fixed doses with regular doses and fixed doses with higher doses

3. We will evaluate the efficacy/safety for these not-well controlled patients.

Study Timeline

• Study Start: 2009-03
• Primary Completion: 2011-02
• Study Completion: 2012-03
• Status Verified: 2012-07
• Study First Submitted: 2012-07-19
• Study First Submitted QC: 2012-07-20
• Study First Posted: 2012-07-23
• Last Update Submitted: 2012-07-23
• Last Update Posted: 2012-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• asthma not well control

Exclusion Criteria

• COPD

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Symbicort	Seretide	We will evaluate the efficacy fot Symbicort use. The usage was 2 doses bid for one year period. Intervention drug: Seretide fixed doses therapy
Seretide	Seretide	In non-well asthma controlled patients, experimental study with Seretide regular doses (125 2 doses bid for one year) and higher doses (250 2 doses bid) for one year

Primary Outcome Measures

Name	Time	Method
the percentage of asthma total and well control	one year	F/U clinical asthma control status and percentage of Acute exacerbation

Secondary Outcome Measures

Name	Time	Method
percentage of asthma acute exacerbation	one year